Cargando…

Matrine inhibits the development and progression of ovarian cancer by repressing cancer associated phosphorylation signaling pathways

Ovarian cancer remains the most lethal gynecologic malignancy with late detection and acquired chemoresistance. Advanced understanding of the pathophysiology and novel treatment strategies are urgently required. A growing body of proteomic investigations suggest that phosphorylation has a pivotal ro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Xi, Hou, Guoqing, Liu, Andong, Xu, Hui, Guan, Yang, Wu, Yaosong, Deng, Jie, Cao, Xuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787190/ https://www.ncbi.nlm.nih.gov/pubmed/31601793 http://dx.doi.org/10.1038/s41419-019-2013-3

Ejemplares similares

Src acts as the target of matrine to inhibit the proliferation of cancer cells by regulating phosphorylation signaling pathways
por: Zhang, Xi, et al.
Publicado: (2021)

Research Progress of Natural Matrine Compounds and Synthetic Matrine Derivatives
por: Li, Jinlei, et al.
Publicado: (2023)

Effects of matrine in combination with cisplatin on liver cancer
por: Hu, Gaoyu, et al.
Publicado: (2021)

Research progress on the pharmacological effects of matrine
por: Sun, Yanan, et al.
Publicado: (2022)

Research Advances on Matrine
por: Sun, Xiao-Ying, et al.
Publicado: (2022)

Treatment mechanism of matrine in combination with irinotecan for colon cancer
por: Duan, Ling, et al.
Publicado: (2017)

Matrine inhibits ovarian cancer cell viability and promotes apoptosis by regulating the ERK/JNK signaling pathway via p38MAPK
por: Liang, Xin, et al.
Publicado: (2021)

Matrine suppresses cardiac fibrosis by inhibiting the TGF-β/Smad pathway in experimental diabetic cardiomyopathy
por: Zhang, Yong, et al.
Publicado: (2018)

Design and Synthesis of Matrine Derivatives as Novel Anti-Pulmonary Fibrotic Agents via Repression of the TGFβ/Smad Pathway
por: Li, Lingyu, et al.
Publicado: (2019)

Matrine inhibits itching by lowering the activity of calcium channel
por: Geng, Xiao, et al.
Publicado: (2018)

LKB1‐MARK2 signalling mediates lipopolysaccharide‐induced production of cytokines in mouse macrophages
por: Deng, Jie, et al.
Publicado: (2020)

Matrine Inhibits CNS Autoimmunity Through an IFN-β-Dependent Mechanism
por: Chu, Yao-Juan, et al.
Publicado: (2020)

Matrine suppresses the migration and invasion of NSCLC cells by inhibiting PAX2-induced epithelial-mesenchymal transition
por: Yang, Jun, et al.
Publicado: (2017)

Matrine suppresses KRAS‐driven pancreatic cancer growth by inhibiting autophagy‐mediated energy metabolism
por: Cho, Young‐ra, et al.
Publicado: (2018)

Matrine suppresses breast cancer metastasis by targeting ITGB1 and inhibiting epithelial-to-mesenchymal transition
por: Ren, Lili, et al.
Publicado: (2020)

Matrine inhibits the migratory and invasive properties of nasopharyngeal carcinoma cells
por: SUN, BIN, et al.
Publicado: (2015)

Matrine Impairs Platelet Function and Thrombosis and Inhibits ROS Production
por: Zhang, Sixuan, et al.
Publicado: (2021)

Matrine prevents bone loss in ovariectomized mice by inhibiting RANKL-induced osteoclastogenesis
por: Chen, Xiao, et al.
Publicado: (2017)

Matrine inhibits TPC-1 human thyroid cancer cells via the miR-21/PTEN/Akt pathway
por: Zhao, Lina, et al.
Publicado: (2018)

Discovery of Matrinic Thiadiazole Derivatives as a Novel Family of Anti-Liver Fibrosis Agents via Repression of the TGFβ/Smad Pathway
por: Niu, Tianyu, et al.
Publicado: (2018)

Matrine inhibits BCR/ABL mediated ERK/MAPK pathway in human leukemia cells
por: Ma, Lingdi, et al.
Publicado: (2017)

Phosphorylation of PHF2 by AMPK releases the repressive H3K9me2 and inhibits cancer metastasis
por: Dong, Ying, et al.
Publicado: (2023)

Exosomal miRNA-139 in cancer-associated fibroblasts inhibits gastric cancer progression by repressing MMP11 expression
por: Xu, Guifang, et al.
Publicado: (2019)

Oxytocin inhibits ovarian cancer metastasis by repressing the expression of MMP-2 and VEGF
por: Ji, Haoyi, et al.
Publicado: (2018)

Repression of Dicer is associated with invasive phenotype and chemoresistance in ovarian cancer
por: KUANG, YAN, et al.
Publicado: (2013)

Anti-Cervical Cancer Role of Matrine, Oxymatrine and Sophora Flavescens Alkaloid Gels and its Mechanism
por: Zhou, Yu Jie, et al.
Publicado: (2018)

Tumor suppressive function of Matrin 3 in the basal-like breast cancer
por: Yang, Jaehyuk, et al.
Publicado: (2020)

Matrine effectively inhibits the proliferation of breast cancer cells through a mechanism related to the NF-κB signaling pathway
por: SHAO, HONGMIN, et al.
Publicado: (2013)

Matrine exerts antitumor activity in cervical cancer by protective autophagy via the Akt/mTOR pathway in vitro and in vivo
por: Zhang, Fan, et al.
Publicado: (2022)

MicroRNA-520g promotes epithelial ovarian cancer progression and chemoresistance via DAPK2 repression
por: Zhang, Jing, et al.
Publicado: (2016)

Sedative Effect of Sophora flavescens and Matrine
por: Lee, Hyun-ju, et al.
Publicado: (2017)

Matrin3: Disorder and ALS Pathogenesis
por: Salem, Ahmed, et al.
Publicado: (2022)

Matrine inhibits the invasive and migratory properties of human hepatocellular carcinoma by regulating epithelial-mesenchymal transition
por: Wang, Yuwen, et al.
Publicado: (2018)

Matrine suppresses lipopolysaccharide-induced fibrosis in human peritoneal mesothelial cells by inhibiting the epithelial-mesenchymal transition
por: Li, Yi-Zheng, et al.
Publicado: (2019)

Matrine inhibits the proliferation, invasion and migration of castration-resistant prostate cancer cells through regulation of the NF-κB signaling pathway
por: LI, QI, et al.
Publicado: (2016)

Matrine Targets Intestinal Lactobacillus acidophilus to Inhibit Porcine Circovirus Type 2 Infection in Mice
por: Cao, Zhigang, et al.
Publicado: (2023)

Matrine Inhibits Neuroblastoma Cell Proliferation and Migration by Enhancing Tribbles 3 Expression
por: Shen, Xiaowei, et al.
Publicado: (2018)

Glucocorticoid receptor repression mediated by BRCA1 inactivation in ovarian cancer
por: Fang, Yuan-Yuan, et al.
Publicado: (2014)

Targeting oxidative phosphorylation as an approach for the treatment of ovarian cancer
por: Wu, Yinjie, et al.
Publicado: (2022)

The Effects of Matrine in Combination with Docetaxel on Castration-Resistant (Androgen-Independent) Prostate Cancer
por: Li, Qi, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_72o2rlr9r6e7umjg97bkbt37t0