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Double Interferometer Design for Independent Wavefront Manipulation in Spectral Domain Optical Coherence Tomography

Spectral domain optical coherence tomography (SD-OCT) is a highly versatile method which allows for three dimensional optical imaging in scattering media. A number of recent publications demonstrated the technique to benefit from structured illumination and beam shaping approaches, e.g. to enhance t...

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Autores principales: Kanngiesser, Jonas, Rahlves, Maik, Roth, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787192/
https://www.ncbi.nlm.nih.gov/pubmed/31601904
http://dx.doi.org/10.1038/s41598-019-50996-2
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author Kanngiesser, Jonas
Rahlves, Maik
Roth, Bernhard
author_facet Kanngiesser, Jonas
Rahlves, Maik
Roth, Bernhard
author_sort Kanngiesser, Jonas
collection PubMed
description Spectral domain optical coherence tomography (SD-OCT) is a highly versatile method which allows for three dimensional optical imaging in scattering media. A number of recent publications demonstrated the technique to benefit from structured illumination and beam shaping approaches, e.g. to enhance the signal-to-noise ratio or the penetration depth with samples such as biological tissue. We present a compact and easy to implement design for independent wavefront manipulation and beam shaping at the reference and sample arm of the interferometric OCT device. The design requires a single spatial light modulator and can be integrated to existing free space SD-OCT systems by modifying the source arm only. We provide analytical and numerical discussion of the presented design as well as experimental data confirming the theoretical analysis. The system is highly versatile and lends itself for applications where independent phase or wavefront control is required. We demonstrate the system to be used for wavefront sensorless adaptive optics as well as for iterative optical wavefront shaping for OCT signal enhancement in strongly scattering media.
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spelling pubmed-67871922019-10-17 Double Interferometer Design for Independent Wavefront Manipulation in Spectral Domain Optical Coherence Tomography Kanngiesser, Jonas Rahlves, Maik Roth, Bernhard Sci Rep Article Spectral domain optical coherence tomography (SD-OCT) is a highly versatile method which allows for three dimensional optical imaging in scattering media. A number of recent publications demonstrated the technique to benefit from structured illumination and beam shaping approaches, e.g. to enhance the signal-to-noise ratio or the penetration depth with samples such as biological tissue. We present a compact and easy to implement design for independent wavefront manipulation and beam shaping at the reference and sample arm of the interferometric OCT device. The design requires a single spatial light modulator and can be integrated to existing free space SD-OCT systems by modifying the source arm only. We provide analytical and numerical discussion of the presented design as well as experimental data confirming the theoretical analysis. The system is highly versatile and lends itself for applications where independent phase or wavefront control is required. We demonstrate the system to be used for wavefront sensorless adaptive optics as well as for iterative optical wavefront shaping for OCT signal enhancement in strongly scattering media. Nature Publishing Group UK 2019-10-10 /pmc/articles/PMC6787192/ /pubmed/31601904 http://dx.doi.org/10.1038/s41598-019-50996-2 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Kanngiesser, Jonas
Rahlves, Maik
Roth, Bernhard
Double Interferometer Design for Independent Wavefront Manipulation in Spectral Domain Optical Coherence Tomography
title Double Interferometer Design for Independent Wavefront Manipulation in Spectral Domain Optical Coherence Tomography
title_full Double Interferometer Design for Independent Wavefront Manipulation in Spectral Domain Optical Coherence Tomography
title_fullStr Double Interferometer Design for Independent Wavefront Manipulation in Spectral Domain Optical Coherence Tomography
title_full_unstemmed Double Interferometer Design for Independent Wavefront Manipulation in Spectral Domain Optical Coherence Tomography
title_short Double Interferometer Design for Independent Wavefront Manipulation in Spectral Domain Optical Coherence Tomography
title_sort double interferometer design for independent wavefront manipulation in spectral domain optical coherence tomography
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787192/
https://www.ncbi.nlm.nih.gov/pubmed/31601904
http://dx.doi.org/10.1038/s41598-019-50996-2
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