Pseudodiabetes—not a contraindication for metabolic interventions

Type-2 diabetes is characterized by glycosuria, hyperglycemia, glucose intolerance, hyperinsulinemia, and insulin resistance. One or several among these alterations are also found after starvation, ketogenic diet, and pharmacological treatment with rapamycin or antibody-mediated neutralization of th...

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Autores principales: Bravo-San Pedro, José Manuel, Sica, Valentina, Kroemer, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787197/
https://www.ncbi.nlm.nih.gov/pubmed/31601789
http://dx.doi.org/10.1038/s41419-019-2007-1
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author Bravo-San Pedro, José Manuel
Sica, Valentina
Kroemer, Guido
author_facet Bravo-San Pedro, José Manuel
Sica, Valentina
Kroemer, Guido
author_sort Bravo-San Pedro, José Manuel
collection PubMed
description Type-2 diabetes is characterized by glycosuria, hyperglycemia, glucose intolerance, hyperinsulinemia, and insulin resistance. One or several among these alterations are also found after starvation, ketogenic diet, and pharmacological treatment with rapamycin or antibody-mediated neutralization of the obesogenic factor ACBP/DBI. Thus, a variety of metabolic interventions that improve metabolic health can induce a transient state of “pseudo-diabetes”.
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spelling pubmed-67871972019-10-11 Pseudodiabetes—not a contraindication for metabolic interventions Bravo-San Pedro, José Manuel Sica, Valentina Kroemer, Guido Cell Death Dis Comment Type-2 diabetes is characterized by glycosuria, hyperglycemia, glucose intolerance, hyperinsulinemia, and insulin resistance. One or several among these alterations are also found after starvation, ketogenic diet, and pharmacological treatment with rapamycin or antibody-mediated neutralization of the obesogenic factor ACBP/DBI. Thus, a variety of metabolic interventions that improve metabolic health can induce a transient state of “pseudo-diabetes”. Nature Publishing Group UK 2019-10-10 /pmc/articles/PMC6787197/ /pubmed/31601789 http://dx.doi.org/10.1038/s41419-019-2007-1 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Comment
Bravo-San Pedro, José Manuel
Sica, Valentina
Kroemer, Guido
Pseudodiabetes—not a contraindication for metabolic interventions
title Pseudodiabetes—not a contraindication for metabolic interventions
title_full Pseudodiabetes—not a contraindication for metabolic interventions
title_fullStr Pseudodiabetes—not a contraindication for metabolic interventions
title_full_unstemmed Pseudodiabetes—not a contraindication for metabolic interventions
title_short Pseudodiabetes—not a contraindication for metabolic interventions
title_sort pseudodiabetes—not a contraindication for metabolic interventions
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787197/
https://www.ncbi.nlm.nih.gov/pubmed/31601789
http://dx.doi.org/10.1038/s41419-019-2007-1
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