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An in-vitro assay using human spermatozoa to detect toxicity of biologically active substances

Identifying the key toxic players within an in-vivo toxic syndrome is crucial to develop targeted therapies. Here, we established a novel method that characterizes the effect of single substances by means of an ex-vivo incubation set-up. We found that primary human spermatozoa elicit a distinct moti...

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Detalles Bibliográficos
Autores principales: Vollmer, Tino, Ljungberg, Börje, Jankowski, Vera, Jankowski, Joachim, Glorieux, Griet, Stegmayr, Bernd G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787250/
https://www.ncbi.nlm.nih.gov/pubmed/31601841
http://dx.doi.org/10.1038/s41598-019-50929-z