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Curvature induction and sensing of the F-BAR protein Pacsin1 on lipid membranes via molecular dynamics simulations

F-Bin/Amphiphysin/Rvs (F-BAR) domain proteins play essential roles in biological processes that involve membrane remodelling, such as endocytosis and exocytosis. It has been shown that such proteins transform the lipid membrane into tubes. Notably, Pacsin1 from the Pacsin/Syndapin subfamily has the...

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Detalles Bibliográficos
Autores principales: Mahmood, Md. Iqbal, Noguchi, Hiroshi, Okazaki, Kei-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787258/
https://www.ncbi.nlm.nih.gov/pubmed/31601944
http://dx.doi.org/10.1038/s41598-019-51202-z