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An Evaluation of DNA Methyltransferase 1 (DNMT1) Single Nucleotide Polymorphisms and Chemotherapy-Associated Cognitive Impairment: A Prospective, Longitudinal Study

Strong evidence suggests that genetic variations in DNA methyltransferases (DNMTs) may alter the downstream expression and DNA methylation patterns of neuronal genes and influence cognition. This study investigates the association between a DNMT1 polymorphism, rs2162560, and chemotherapy-associated...

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Detalles Bibliográficos
Autores principales: Chan, Alexandre, Yeo, Angie, Shwe, Maung, Tan, Chia Jie, Foo, Koon Mian, Chu, Pat, Khor, Chiea Chuen, Ho, Han Kiat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787348/
https://www.ncbi.nlm.nih.gov/pubmed/31601979
http://dx.doi.org/10.1038/s41598-019-51203-y

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