A Newborn Female with a Diffuse Rash

Langerhans cell histiocytosis is a rare and clinically heterogeneous group of dendritic histiocytic disorders with typical onset in the neonatal period or infancy, although it can present at any age. Histiocytes accumulate in one or more organs, leading to a variable clinical presentation of disease...

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Detalles Bibliográficos
Autores principales: Holcomb, Zachary E., Yu, Sherry H., Menge, Tyler D., Nazarian, Rosalynn M., Jessup, Chad J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787425/
https://www.ncbi.nlm.nih.gov/pubmed/31616659
http://dx.doi.org/10.1159/000501787
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author Holcomb, Zachary E.
Yu, Sherry H.
Menge, Tyler D.
Nazarian, Rosalynn M.
Jessup, Chad J.
author_facet Holcomb, Zachary E.
Yu, Sherry H.
Menge, Tyler D.
Nazarian, Rosalynn M.
Jessup, Chad J.
author_sort Holcomb, Zachary E.
collection PubMed
description Langerhans cell histiocytosis is a rare and clinically heterogeneous group of dendritic histiocytic disorders with typical onset in the neonatal period or infancy, although it can present at any age. Histiocytes accumulate in one or more organs, leading to a variable clinical presentation of disease. We report a case of biopsy-proven Langerhans cell histiocytosis in a newborn and discuss the workup and management of this disease, along with reviewing its clinical variants.
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spelling pubmed-67874252019-10-15 A Newborn Female with a Diffuse Rash Holcomb, Zachary E. Yu, Sherry H. Menge, Tyler D. Nazarian, Rosalynn M. Jessup, Chad J. Dermatopathology (Basel) Case Report Langerhans cell histiocytosis is a rare and clinically heterogeneous group of dendritic histiocytic disorders with typical onset in the neonatal period or infancy, although it can present at any age. Histiocytes accumulate in one or more organs, leading to a variable clinical presentation of disease. We report a case of biopsy-proven Langerhans cell histiocytosis in a newborn and discuss the workup and management of this disease, along with reviewing its clinical variants. S. Karger AG 2019-09-04 /pmc/articles/PMC6787425/ /pubmed/31616659 http://dx.doi.org/10.1159/000501787 Text en Copyright © 2019 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Holcomb, Zachary E.
Yu, Sherry H.
Menge, Tyler D.
Nazarian, Rosalynn M.
Jessup, Chad J.
A Newborn Female with a Diffuse Rash
title A Newborn Female with a Diffuse Rash
title_full A Newborn Female with a Diffuse Rash
title_fullStr A Newborn Female with a Diffuse Rash
title_full_unstemmed A Newborn Female with a Diffuse Rash
title_short A Newborn Female with a Diffuse Rash
title_sort newborn female with a diffuse rash
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787425/
https://www.ncbi.nlm.nih.gov/pubmed/31616659
http://dx.doi.org/10.1159/000501787
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