Glucocorticoid receptor inhibits Müller glial galectin‐1 expression via DUSP1‐dependent and ‐independent deactivation of AP‐1 signalling

Galectin‐1/LGALS1 is a hypoxia‐induced angiogenic factor associated with diabetic retinopathy (DR). Recently, we elucidated a hypoxia‐independent pathway to produce galectin‐1 in Müller glial cells stimulated by interleukin (IL)‐1β. Here we revealed glucocorticoid receptor (GR)‐mediated inhibitory m...

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Detalles Bibliográficos
Autores principales: Hirose, Ikuyo, Kanda, Atsuhiro, Noda, Kousuke, Ishida, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787449/
https://www.ncbi.nlm.nih.gov/pubmed/31328390
http://dx.doi.org/10.1111/jcmm.14559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787449/
https://www.ncbi.nlm.nih.gov/pubmed/31328390
http://dx.doi.org/10.1111/jcmm.14559

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