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A Library Screening Strategy Combining the Concepts of MS Binding Assays and Affinity Selection Mass Spectrometry

The primary objective of early drug development is to identify hits and leads for a target of interest. To achieve this aim, rapid, and reliable screening techniques for a huge number of compounds are needed. Mass spectrometry based binding assays (MS Binding Assays) represent a well-established tec...

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Detalles Bibliográficos
Autores principales: Gabriel, Jürgen, Höfner, Georg, Wanner, Klaus T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787468/
https://www.ncbi.nlm.nih.gov/pubmed/31637233
http://dx.doi.org/10.3389/fchem.2019.00665