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A Library Screening Strategy Combining the Concepts of MS Binding Assays and Affinity Selection Mass Spectrometry
The primary objective of early drug development is to identify hits and leads for a target of interest. To achieve this aim, rapid, and reliable screening techniques for a huge number of compounds are needed. Mass spectrometry based binding assays (MS Binding Assays) represent a well-established tec...
Autores principales: | Gabriel, Jürgen, Höfner, Georg, Wanner, Klaus T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787468/ https://www.ncbi.nlm.nih.gov/pubmed/31637233 http://dx.doi.org/10.3389/fchem.2019.00665 |
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