Identification of predictive genetic signatures of Cytarabine responsiveness using a 3D acute myeloid leukaemia model

This study reports the establishment of a bone marrow mononuclear cell (BMMC) 3D culture model and the application of this model to define sensitivity and resistance biomarkers of acute myeloid leukaemia (AML) patient bone marrow samples in response to Cytarabine (Ara‐C) treatment. By mimicking phys...

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Detalles Bibliográficos
Autores principales: Xu, Haiyan, Muise, Eric S., Javaid, Sarah, Chen, Lan, Cristescu, Razvan, Mansueto, My Sam, Follmer, Nicole, Cho, Jennifer, Kerr, Kimberley, Altura, Rachel, Machacek, Michelle, Nicholson, Benjamin, Addona, George, Kariv, Ilona, Chen, Hongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787505/
https://www.ncbi.nlm.nih.gov/pubmed/31449347
http://dx.doi.org/10.1111/jcmm.14608

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787505/
https://www.ncbi.nlm.nih.gov/pubmed/31449347
http://dx.doi.org/10.1111/jcmm.14608

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