MetaMed: Linking Microbiota Functions with Medicine Therapeutics

Understanding how the human microbiome affects human health has consequences for treating disease and minimizing unwanted side effects in clinical research. Here, we present MetaMed (http://metamed.rwebox.com/index), a novel and integrative system-wide correlation mapping system to link bacterial fu...

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Detalles Bibliográficos
Autores principales: Zhao, Han, Fu, Shaliu, Yu, Yifei, Zhang, Zhanbing, Li, Ping, Ma, Qin, Jia, Wei, Ning, Kang, Qu, Shen, Liu, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Opinion/Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787565/
https://www.ncbi.nlm.nih.gov/pubmed/31594829
http://dx.doi.org/10.1128/mSystems.00413-19
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author Zhao, Han
Fu, Shaliu
Yu, Yifei
Zhang, Zhanbing
Li, Ping
Ma, Qin
Jia, Wei
Ning, Kang
Qu, Shen
Liu, Qi
author_facet Zhao, Han
Fu, Shaliu
Yu, Yifei
Zhang, Zhanbing
Li, Ping
Ma, Qin
Jia, Wei
Ning, Kang
Qu, Shen
Liu, Qi
author_sort Zhao, Han
collection PubMed
description Understanding how the human microbiome affects human health has consequences for treating disease and minimizing unwanted side effects in clinical research. Here, we present MetaMed (http://metamed.rwebox.com/index), a novel and integrative system-wide correlation mapping system to link bacterial functions and medicine therapeutics, providing novel hypotheses for deep investigation of microbe therapeutic effects on human health. Furthermore, comprehensive relationships between microbes living in the environment and drugs were discovered, providing a rich source for discovering microbiota metabolites with great potential for pharmaceutical applications.
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spelling pubmed-67875652019-10-15 MetaMed: Linking Microbiota Functions with Medicine Therapeutics Zhao, Han Fu, Shaliu Yu, Yifei Zhang, Zhanbing Li, Ping Ma, Qin Jia, Wei Ning, Kang Qu, Shen Liu, Qi mSystems Opinion/Hypothesis Understanding how the human microbiome affects human health has consequences for treating disease and minimizing unwanted side effects in clinical research. Here, we present MetaMed (http://metamed.rwebox.com/index), a novel and integrative system-wide correlation mapping system to link bacterial functions and medicine therapeutics, providing novel hypotheses for deep investigation of microbe therapeutic effects on human health. Furthermore, comprehensive relationships between microbes living in the environment and drugs were discovered, providing a rich source for discovering microbiota metabolites with great potential for pharmaceutical applications. American Society for Microbiology 2019-10-08 /pmc/articles/PMC6787565/ /pubmed/31594829 http://dx.doi.org/10.1128/mSystems.00413-19 Text en Copyright © 2019 Zhao et al. https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Opinion/Hypothesis
Zhao, Han
Fu, Shaliu
Yu, Yifei
Zhang, Zhanbing
Li, Ping
Ma, Qin
Jia, Wei
Ning, Kang
Qu, Shen
Liu, Qi
MetaMed: Linking Microbiota Functions with Medicine Therapeutics
title MetaMed: Linking Microbiota Functions with Medicine Therapeutics
title_full MetaMed: Linking Microbiota Functions with Medicine Therapeutics
title_fullStr MetaMed: Linking Microbiota Functions with Medicine Therapeutics
title_full_unstemmed MetaMed: Linking Microbiota Functions with Medicine Therapeutics
title_short MetaMed: Linking Microbiota Functions with Medicine Therapeutics
title_sort metamed: linking microbiota functions with medicine therapeutics
topic Opinion/Hypothesis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787565/
https://www.ncbi.nlm.nih.gov/pubmed/31594829
http://dx.doi.org/10.1128/mSystems.00413-19
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