Long-Lasting Remission in De Novo Breast Myeloid Sarcoma Treated with Decitabine and Radiotherapy

Myeloid sarcoma (MS) represents a rare disease with an adverse clinical outcome for patients not candidate to acute myeloid leukemia (AML)-like chemotherapies. Here we present the case of an elderly patient affected by a bilateral breast localization of MS treated with the hypomethylating agent deci...

Descripción completa

Detalles Bibliográficos
Autores principales: Minoia, Carla, de Fazio, Vincenza, Scognamillo, Giovanni, Scattone, Anna, Maggialetti, Nicola, Ferrari, Cristina, Guarini, Attilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787642/
https://www.ncbi.nlm.nih.gov/pubmed/31357576
http://dx.doi.org/10.3390/diagnostics9030084
_version_ 1783458312676704256
author Minoia, Carla
de Fazio, Vincenza
Scognamillo, Giovanni
Scattone, Anna
Maggialetti, Nicola
Ferrari, Cristina
Guarini, Attilio
author_facet Minoia, Carla
de Fazio, Vincenza
Scognamillo, Giovanni
Scattone, Anna
Maggialetti, Nicola
Ferrari, Cristina
Guarini, Attilio
author_sort Minoia, Carla
collection PubMed
description Myeloid sarcoma (MS) represents a rare disease with an adverse clinical outcome for patients not candidate to acute myeloid leukemia (AML)-like chemotherapies. Here we present the case of an elderly patient affected by a bilateral breast localization of MS treated with the hypomethylating agent decitabine associated to radiotherapy. The association of the two treatment modalities has allowed an optimal and long-lasting disease control.
format Online
Article
Text
id pubmed-6787642
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-67876422019-10-16 Long-Lasting Remission in De Novo Breast Myeloid Sarcoma Treated with Decitabine and Radiotherapy Minoia, Carla de Fazio, Vincenza Scognamillo, Giovanni Scattone, Anna Maggialetti, Nicola Ferrari, Cristina Guarini, Attilio Diagnostics (Basel) Case Report Myeloid sarcoma (MS) represents a rare disease with an adverse clinical outcome for patients not candidate to acute myeloid leukemia (AML)-like chemotherapies. Here we present the case of an elderly patient affected by a bilateral breast localization of MS treated with the hypomethylating agent decitabine associated to radiotherapy. The association of the two treatment modalities has allowed an optimal and long-lasting disease control. MDPI 2019-07-27 /pmc/articles/PMC6787642/ /pubmed/31357576 http://dx.doi.org/10.3390/diagnostics9030084 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Minoia, Carla
de Fazio, Vincenza
Scognamillo, Giovanni
Scattone, Anna
Maggialetti, Nicola
Ferrari, Cristina
Guarini, Attilio
Long-Lasting Remission in De Novo Breast Myeloid Sarcoma Treated with Decitabine and Radiotherapy
title Long-Lasting Remission in De Novo Breast Myeloid Sarcoma Treated with Decitabine and Radiotherapy
title_full Long-Lasting Remission in De Novo Breast Myeloid Sarcoma Treated with Decitabine and Radiotherapy
title_fullStr Long-Lasting Remission in De Novo Breast Myeloid Sarcoma Treated with Decitabine and Radiotherapy
title_full_unstemmed Long-Lasting Remission in De Novo Breast Myeloid Sarcoma Treated with Decitabine and Radiotherapy
title_short Long-Lasting Remission in De Novo Breast Myeloid Sarcoma Treated with Decitabine and Radiotherapy
title_sort long-lasting remission in de novo breast myeloid sarcoma treated with decitabine and radiotherapy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787642/
https://www.ncbi.nlm.nih.gov/pubmed/31357576
http://dx.doi.org/10.3390/diagnostics9030084
work_keys_str_mv AT minoiacarla longlastingremissionindenovobreastmyeloidsarcomatreatedwithdecitabineandradiotherapy
AT defaziovincenza longlastingremissionindenovobreastmyeloidsarcomatreatedwithdecitabineandradiotherapy
AT scognamillogiovanni longlastingremissionindenovobreastmyeloidsarcomatreatedwithdecitabineandradiotherapy
AT scattoneanna longlastingremissionindenovobreastmyeloidsarcomatreatedwithdecitabineandradiotherapy
AT maggialettinicola longlastingremissionindenovobreastmyeloidsarcomatreatedwithdecitabineandradiotherapy
AT ferraricristina longlastingremissionindenovobreastmyeloidsarcomatreatedwithdecitabineandradiotherapy
AT guariniattilio longlastingremissionindenovobreastmyeloidsarcomatreatedwithdecitabineandradiotherapy

Ejemplares similares