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Power and Design Issues in Crossover-Based N-Of-1 Clinical Trials with Fixed Data Collection Periods
“N-of-1,” or single subject, clinical trials seek to determine if an intervention strategy is more efficacious for an individual than an alternative based on an objective, empirical, and controlled study. The design of such trials is typically rooted in a simple crossover strategy with multiple inte...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787650/ https://www.ncbi.nlm.nih.gov/pubmed/31269712 http://dx.doi.org/10.3390/healthcare7030084 |