Tendon rupture associated with concomitant simvastatin and gemfibrozil use: Biological and pharmacokinetic implications

Tendon or muscle rupture is a rare complication of statins that could potentially be disabling and result in a significant burden to patients. The co‐administration of statin and gemfibrozil should warrant prescribers’ awareness of tendon‐related complications of statin use, particularly in high‐ris...

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Detalles Bibliográficos
Autores principales: Cano Cevallos, Edison Jose, Shaikh, Danial Haris, Gonzalez, Jose, Sanchez, William, Patel, Madanmohan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787793/
https://www.ncbi.nlm.nih.gov/pubmed/31624609
http://dx.doi.org/10.1002/ccr3.2387
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author Cano Cevallos, Edison Jose
Shaikh, Danial Haris
Gonzalez, Jose
Sanchez, William
Patel, Madanmohan
author_facet Cano Cevallos, Edison Jose
Shaikh, Danial Haris
Gonzalez, Jose
Sanchez, William
Patel, Madanmohan
author_sort Cano Cevallos, Edison Jose
collection PubMed
description Tendon or muscle rupture is a rare complication of statins that could potentially be disabling and result in a significant burden to patients. The co‐administration of statin and gemfibrozil should warrant prescribers’ awareness of tendon‐related complications of statin use, particularly in high‐risk populations with poor renal function or musculoskeletal comorbidities.
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spelling pubmed-67877932019-10-17 Tendon rupture associated with concomitant simvastatin and gemfibrozil use: Biological and pharmacokinetic implications Cano Cevallos, Edison Jose Shaikh, Danial Haris Gonzalez, Jose Sanchez, William Patel, Madanmohan Clin Case Rep Case Reports Tendon or muscle rupture is a rare complication of statins that could potentially be disabling and result in a significant burden to patients. The co‐administration of statin and gemfibrozil should warrant prescribers’ awareness of tendon‐related complications of statin use, particularly in high‐risk populations with poor renal function or musculoskeletal comorbidities. John Wiley and Sons Inc. 2019-08-28 /pmc/articles/PMC6787793/ /pubmed/31624609 http://dx.doi.org/10.1002/ccr3.2387 Text en © 2019 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Cano Cevallos, Edison Jose
Shaikh, Danial Haris
Gonzalez, Jose
Sanchez, William
Patel, Madanmohan
Tendon rupture associated with concomitant simvastatin and gemfibrozil use: Biological and pharmacokinetic implications
title Tendon rupture associated with concomitant simvastatin and gemfibrozil use: Biological and pharmacokinetic implications
title_full Tendon rupture associated with concomitant simvastatin and gemfibrozil use: Biological and pharmacokinetic implications
title_fullStr Tendon rupture associated with concomitant simvastatin and gemfibrozil use: Biological and pharmacokinetic implications
title_full_unstemmed Tendon rupture associated with concomitant simvastatin and gemfibrozil use: Biological and pharmacokinetic implications
title_short Tendon rupture associated with concomitant simvastatin and gemfibrozil use: Biological and pharmacokinetic implications
title_sort tendon rupture associated with concomitant simvastatin and gemfibrozil use: biological and pharmacokinetic implications
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787793/
https://www.ncbi.nlm.nih.gov/pubmed/31624609
http://dx.doi.org/10.1002/ccr3.2387
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