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Lichen planus with multiple system involvement including the mouth, vagina, urethra, and scalp: a case report
This is a case report of lichen planus (LP) with multiple system involvement. A 35-year-old female patient was admitted in November 2014 with a 5-year history of painful/difficult sexual intercourse and loss of oral mucosa, and an 8-year history of focal hair loss. Earlier, the patient had been unab...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Associação Brasileira de Divulgação Científica
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787949/ https://www.ncbi.nlm.nih.gov/pubmed/31618369 http://dx.doi.org/10.1590/1414-431X20198823 |
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author | Mi, Lan Zhang, Hong Zhang, Dai Zhang, Miao |
author_facet | Mi, Lan Zhang, Hong Zhang, Dai Zhang, Miao |
author_sort | Mi, Lan |
collection | PubMed |
description | This is a case report of lichen planus (LP) with multiple system involvement. A 35-year-old female patient was admitted in November 2014 with a 5-year history of painful/difficult sexual intercourse and loss of oral mucosa, and an 8-year history of focal hair loss. Earlier, the patient had been unable to adhere to corticosteroid therapy because of severe adverse side effects. In September 2014, labia minora mucosa defects and stricture of the urethral orifice (with dysuria), vaginal orifice, and vagina were identified. Biopsy was performed and a diagnosis of erosive LP was made. The patient was treated with an oral immunosuppressant (cyclosporine A) and urethral/vaginal dilatation. Urine flow rate and sex life were improved after 6 months and she discontinued medication. Four years later, the patient reported a good overall treatment efficacy. LP can involve multiple systems and should be considered in patients with dyspareunia. Immunosuppressive agents can achieve a satisfactory effect in patients with contraindication to corticosteroid. |
format | Online Article Text |
id | pubmed-6787949 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Associação Brasileira de Divulgação Científica |
record_format | MEDLINE/PubMed |
spelling | pubmed-67879492019-10-21 Lichen planus with multiple system involvement including the mouth, vagina, urethra, and scalp: a case report Mi, Lan Zhang, Hong Zhang, Dai Zhang, Miao Braz J Med Biol Res Case Report This is a case report of lichen planus (LP) with multiple system involvement. A 35-year-old female patient was admitted in November 2014 with a 5-year history of painful/difficult sexual intercourse and loss of oral mucosa, and an 8-year history of focal hair loss. Earlier, the patient had been unable to adhere to corticosteroid therapy because of severe adverse side effects. In September 2014, labia minora mucosa defects and stricture of the urethral orifice (with dysuria), vaginal orifice, and vagina were identified. Biopsy was performed and a diagnosis of erosive LP was made. The patient was treated with an oral immunosuppressant (cyclosporine A) and urethral/vaginal dilatation. Urine flow rate and sex life were improved after 6 months and she discontinued medication. Four years later, the patient reported a good overall treatment efficacy. LP can involve multiple systems and should be considered in patients with dyspareunia. Immunosuppressive agents can achieve a satisfactory effect in patients with contraindication to corticosteroid. Associação Brasileira de Divulgação Científica 2019-10-10 /pmc/articles/PMC6787949/ /pubmed/31618369 http://dx.doi.org/10.1590/1414-431X20198823 Text en https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Mi, Lan Zhang, Hong Zhang, Dai Zhang, Miao Lichen planus with multiple system involvement including the mouth, vagina, urethra, and scalp: a case report |
title | Lichen planus with multiple system involvement including the mouth, vagina, urethra, and scalp: a case report |
title_full | Lichen planus with multiple system involvement including the mouth, vagina, urethra, and scalp: a case report |
title_fullStr | Lichen planus with multiple system involvement including the mouth, vagina, urethra, and scalp: a case report |
title_full_unstemmed | Lichen planus with multiple system involvement including the mouth, vagina, urethra, and scalp: a case report |
title_short | Lichen planus with multiple system involvement including the mouth, vagina, urethra, and scalp: a case report |
title_sort | lichen planus with multiple system involvement including the mouth, vagina, urethra, and scalp: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787949/ https://www.ncbi.nlm.nih.gov/pubmed/31618369 http://dx.doi.org/10.1590/1414-431X20198823 |
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