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Dietary intakes and biomarker patterns of folate, vitamin B(6), and vitamin B(12) can be associated with cognitive impairment by hypermethylation of redox-related genes NUDT15 and TXNRD1
BACKGROUND: B vitamins in the one-carbon metabolism pathway (folate, vitamin B(6), and vitamin B(12)) have been implicated in DNA methylation, and their deficiency may contribute to cognitive decline through increased homocysteine (Hcy) levels and subsequent oxidative damage. The aim of this study w...
Autores principales: | An, Yu, Feng, Lingli, Zhang, Xiaona, Wang, Ying, Wang, Yushan, Tao, Lingwei, Qin, Zhongsheng, Xiao, Rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787977/ https://www.ncbi.nlm.nih.gov/pubmed/31601260 http://dx.doi.org/10.1186/s13148-019-0741-y |
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