Allogeneic hematopoietic stem cell transplantation in two brothers with DNA ligase IV deficiency: a case report and review of the literature

BACKGROUND: DNA ligase IV deficiency is a rare autosomal recessive disorder caused by hypomorphic mutations in the DNA ligase IV (LIG4) gene. DNA ligase IV is an essential protein for the development of a healthy immune system as well as for the protection of genomic integrity. Apart from typical st...

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Detalles Bibliográficos
Autores principales: Schober, Sarah, Schilbach, Karin, Doering, Michaela, Cabanillas Stanchi, Karin M., Holzer, Ursula, Kasteleiner, Patrick, Schittenhelm, Jens, Schaefer, Juergen F., Mueller, Ingo, Lang, Peter, Handgretinger, Rupert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788020/
https://www.ncbi.nlm.nih.gov/pubmed/31604460
http://dx.doi.org/10.1186/s12887-019-1724-z

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