Plasma neurofilament light chain and amyloid-β are associated with the kynurenine pathway metabolites in preclinical Alzheimer’s disease

BACKGROUND: Blood markers indicative of neurodegeneration (neurofilament light chain; NFL), Alzheimer’s disease amyloid pathology (amyloid-β; Aβ), and neuroinflammation (kynurenine pathway; KP metabolites) have been investigated independently in neurodegenerative diseases. However, the association o...

Descripción completa

Detalles Bibliográficos
Autores principales: Chatterjee, Pratishtha, Zetterberg, Henrik, Goozee, Kathryn, Lim, Chai K., Jacobs, Kelly R., Ashton, Nicholas J., Hye, Abdul, Pedrini, Steve, Sohrabi, Hamid R., Shah, Tejal, Asih, Prita R., Dave, Preeti, Shen, Kaikai, Taddei, Kevin, Lovejoy, David B., Guillemin, Gilles J., Blennow, Kaj, Martins, Ralph N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788092/
https://www.ncbi.nlm.nih.gov/pubmed/31601232
http://dx.doi.org/10.1186/s12974-019-1567-4

Ejemplares similares

Ejemplares similares