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Propofol Induces Cardioprotection Against Ischemia-Reperfusion Injury via Suppression of Transient Receptor Potential Vanilloid 4 Channel

Ca(2+) entry via the transient receptor potential vanilloid 4 (TRPV4) channel contributes to Ca(2+) overload and triggers many pathophysiological conditions, including myocardial ischemia/reperfusion (I/R) injury. Propofol, a widely used intravenous anesthetic, attenuates myocardial I/R injury. Howe...

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Detalles Bibliográficos
Autores principales:	Wang, Binbin, Wu, Qiongfeng, Liao, Jie, Zhang, Shaoshao, Liu, Huixia, Yang, Cui, Dong, Qian, Zhao, Ning, Huang, Zhengrong, Guo, Kefang, Du, Yimei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788301/ https://www.ncbi.nlm.nih.gov/pubmed/31636563 http://dx.doi.org/10.3389/fphar.2019.01150

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