Cargando…

SERPIND1 Affects the Malignant Biological Behavior of Epithelial Ovarian Cancer via the PI3K/AKT Pathway: A Mechanistic Study

Serpin family D member 1 (SERPIND1) belongs to the serine protease inhibitor family. Its role in cancers has gradually attracted interest from researchers in recent years. However, the role of SERPIND1 in the development of epithelial ovarian cancer remains poorly understood. This studied aimed to i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guo, Qian, Zhu, Liancheng, Wang, Caixia, Wang, Shuang, Nie, Xin, Liu, Juanjuan, Liu, Qing, Hao, Yingying, Li, Xiao, Lin, Bei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788328/ https://www.ncbi.nlm.nih.gov/pubmed/31637210 http://dx.doi.org/10.3389/fonc.2019.00954

Ejemplares similares

YWHAE as an HE4 interacting protein can influence the malignant behaviour of ovarian cancer by regulating the PI3K/AKT and MAPK pathways
por: Li, Xiao, et al.
Publicado: (2021)

Lewis y antigen promotes the proliferation of ovarian carcinoma-derived RMG-I cells through the PI3K/Akt signaling pathway
por: Liu, Juanjuan, et al.
Publicado: (2009)

Low BCL9 expression inhibited ovarian epithelial malignant tumor progression by decreasing proliferation, migration, and increasing apoptosis to cancer cells
por: Wang, Jing, et al.
Publicado: (2019)

HERPUD1 promotes ovarian cancer cell survival by sustaining autophagy and inhibit apoptosis via PI3K/AKT/mTOR and p38 MAPK signaling pathways
por: Nie, Xin, et al.
Publicado: (2022)

Down-regulation of TRIB3 inhibits the progression of ovarian cancer via MEK/ERK signaling pathway
por: Wang, Shuang, et al.
Publicado: (2020)

Overexpression of TMEFF1 in Endometrial Carcinoma and the Mechanism Underlying its Promotion of Malignant Behavior in Cancer Cells
por: Nie, Xin, et al.
Publicado: (2021)

Gene expression profile analysis identifies metastasis and chemoresistance-associated genes in epithelial ovarian carcinoma cells
por: Zhu, Liancheng, et al.
Publicado: (2014)

ZNF703 promotes tumor progression in ovarian cancer by interacting with HE4 and epigenetically regulating PEA15
por: Wang, Shuang, et al.
Publicado: (2020)

The fucosylated CD147 enhances the autophagy in epithelial ovarian cancer cells
por: Hu, Zhenhua, et al.
Publicado: (2016)

Annexin A4 fucosylation enhances its interaction with the NF-kB p50 and promotes tumor progression of ovarian clear cell carcinoma
por: Wang, Huimin, et al.
Publicado: (2016)

Identification of PKP 2/3 as potential biomarkers of ovarian cancer based on bioinformatics and experiments
por: Gao, Lingling, et al.
Publicado: (2020)

Chemoresistance Is Associated with MUC1 and Lewis y Antigen Expression in Ovarian Epithelial Cancers
por: Zhang, Danye, et al.
Publicado: (2013)

TRPM7 promotes the epithelial–mesenchymal transition in ovarian cancer through the calcium-related PI3K / AKT oncogenic signaling
por: Liu, Lu, et al.
Publicado: (2019)

Co-expression of Lewis y antigen and CD147 in epithelial ovarian cancer is correlated with malignant progression and poor prognosis
por: Liu, Juanjuan, et al.
Publicado: (2019)

UBE2T regulates epithelial–mesenchymal transition through the PI3K-AKT pathway and plays a carcinogenic role in ovarian cancer
por: Cui, Ping, et al.
Publicado: (2022)

Identification and clinical validation of NUSAP1 as a novel prognostic biomarker in ovarian cancer
por: Gou, Rui, et al.
Publicado: (2022)

Increase in Docetaxel-Resistance of Ovarian Carcinoma-Derived RMG-1 Cells with Enhanced Expression of Lewis Y Antigen
por: Zhang, Fan, et al.
Publicado: (2011)

Lewis Y Promotes Growth and Adhesion of Ovarian Carcinoma-Derived RMG-I Cells by Upregulating Growth Factors
por: Li, Feifei, et al.
Publicado: (2010)

Carvedilol suppresses malignant proliferation of mammary epithelial cells through inhibition of the ROS-mediated PI3K/AKT signaling pathway
por: Ma, Zhongbing, et al.
Publicado: (2019)

EPDR1, Which Is Negatively Regulated by miR-429, Suppresses Epithelial Ovarian Cancer Progression via PI3K/AKT Signaling Pathway
por: Zhao, Zhendan, et al.
Publicado: (2021)

Targeting the PI3K/AKT/mTOR pathway in epithelial ovarian cancer, therapeutic treatment options for platinum-resistant ovarian cancer
por: Rinne, Natasha, et al.
Publicado: (2021)

c-Fos mediates α1, 2-fucosyltransferase 1 and Lewis y expression in response to TGF-β1 in ovarian cancer
por: Hao, Yingying, et al.
Publicado: (2017)

PIM Kinases and Their Relevance to the PI3K/AKT/mTOR Pathway in the Regulation of Ovarian Cancer
por: Aziz, Aziz Ur Rehman, et al.
Publicado: (2018)

CCL25/CCR9 interaction promotes the malignant behavior of salivary adenoid cystic carcinoma via the PI3K/AKT signaling pathway
por: Chai, Songling, et al.
Publicado: (2022)

The Stimulation of IGF-1R Expression by Lewis(y) Antigen Provides a Powerful Development Mechanism of Epithelial Ovarian Carcinoma
por: Liu, Dawo, et al.
Publicado: (2011)

Targeting ACLY Attenuates Tumor Growth and Acquired Cisplatin Resistance in Ovarian Cancer by Inhibiting the PI3K–AKT Pathway and Activating the AMPK–ROS Pathway
por: Wei, Xuan, et al.
Publicado: (2021)

The Importance of the PI3K/AKT/MTOR Pathway in the Progression of Ovarian Cancer
por: Dobbin, Zachary C., et al.
Publicado: (2013)

Comparing PI3K/Akt Inhibitors Used in Ovarian Cancer Treatment
por: Wu, Yi-Hui, et al.
Publicado: (2020)

Protopine triggers apoptosis via the intrinsic pathway and regulation of ROS/PI3K/Akt signalling pathway in liver carcinoma
por: Nie, Chunhui, et al.
Publicado: (2021)

Lanthanum Chloride Sensitizes Cisplatin Resistance of Ovarian Cancer Cells via PI3K/Akt Pathway
por: Fang, Shanyu, et al.
Publicado: (2021)

Role of PI3K/AKT pathway in cancer: the framework of malignant behavior
por: Jiang, Ningni, et al.
Publicado: (2020)

Tetraspanin 1 promotes epithelial-to-mesenchymal transition and metastasis of cholangiocarcinoma via PI3K/AKT signaling
por: Wang, Yan, et al.
Publicado: (2018)

P4HA2 Promotes Epithelial-to-Mesenchymal Transition and Glioma Malignancy through the Collagen-Dependent PI3K/AKT Pathway
por: Lin, Jing, et al.
Publicado: (2021)

Corrigendum: Targeting ACLY Attenuates Tumor Growth and Acquired Cisplatin Resistance in Ovarian Cancer by Inhibiting the PI3K–AKT Pathway and Activating the AMPK–ROS Pathway
por: Wei, Xuan, et al.
Publicado: (2021)

SLC25A32 promotes malignant progression of glioblastoma by activating PI3K-AKT signaling pathway
por: Xue, Zhiwei, et al.
Publicado: (2023)

Embryonic stem cell microenvironment suppresses the malignancy of cutaneous melanoma cells by down‐regulating PI3K/AKT pathway
por: Wang, Chenjie, et al.
Publicado: (2019)

MicroRNA-936 targets FGF2 to inhibit epithelial ovarian cancer aggressiveness by deactivating the PI3K/Akt pathway
por: Li, Cuihong, et al.
Publicado: (2019)

Tanshinone IIA affects the malignant growth of Cholangiocarcinoma cells by inhibiting the PI3K-Akt-mTOR pathway
por: Liu, Huayuan, et al.
Publicado: (2021)

Lewis y Regulate Cell Cycle Related Factors in Ovarian Carcinoma Cell RMG-I in Vitro via ERK and Akt Signaling Pathways
por: Liu, Dawo, et al.
Publicado: (2012)

Overexpression of HE4 (human epididymis protein 4) enhances proliferation, invasion and metastasis of ovarian cancer
por: Zhu, Liancheng, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_e9ln1ir4n751kt85lsl4pjf1mt