Cargando…

The Effect of a Common Daily Schedule on Human Circadian Rhythms During the Polar Day in Svalbard: A Field Study

All Arctic visitors have to deal with extreme conditions, including a constant high light intensity during the summer season or constant darkness during winter. The light/dark cycle serves as the most potent synchronizing signal for the biological clock, and any Arctic visitor attending those region...

Descripción completa

Detalles Bibliográficos
Autores principales: Weissová, Kamila, Škrabalová, Jitka, Skálová, Kateřina, Bendová, Zdeňka, Kopřivová, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ubiquity Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788356/
https://www.ncbi.nlm.nih.gov/pubmed/31656532
http://dx.doi.org/10.5334/jcr.186
_version_ 1783458470012387328
author Weissová, Kamila
Škrabalová, Jitka
Skálová, Kateřina
Bendová, Zdeňka
Kopřivová, Jana
author_facet Weissová, Kamila
Škrabalová, Jitka
Skálová, Kateřina
Bendová, Zdeňka
Kopřivová, Jana
author_sort Weissová, Kamila
collection PubMed
description All Arctic visitors have to deal with extreme conditions, including a constant high light intensity during the summer season or constant darkness during winter. The light/dark cycle serves as the most potent synchronizing signal for the biological clock, and any Arctic visitor attending those regions during winter or summer would struggle with the absence of those entraining signals. However, the inner clock can be synchronized by other zeitgebers such as physical activity, food intake, or social interactions. Here, we investigated the effect of the polar day on the circadian clock of 10 researchers attending the polar base station in the Svalbard region during the summer season. The data collected in Svalbard was compared with data obtained just before leaving for the expedition (in the Czech Republic 49.8175°N, 15.4730°E). To determine the circadian functions, we monitored activity/rest rhythm with wrist actigraphy followed by sleep diaries, melatonin rhythm in saliva, and clock gene expression (Per1, Bmal1, and Nr1D1) in buccal mucosa samples. Our data shows that the two-week stay in Svalbard delayed melatonin onset but did not affect its rhythmic secretion, and delayed the activity/rest rhythm. Furthermore, the clock gene expression displayed a higher amplitude in Svalbard compared to the amplitude detected in the Czech Republic. We hypothesize that the common daily schedule at the Svalbard expedition strengthens circadian rhythmicity even in conditions of compromised light/dark cycles. To our knowledge, this is the first study to demonstrate peripheral clock gene expression during a polar expedition.
format Online
Article
Text
id pubmed-6788356
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Ubiquity Press
record_format MEDLINE/PubMed
spelling pubmed-67883562019-10-25 The Effect of a Common Daily Schedule on Human Circadian Rhythms During the Polar Day in Svalbard: A Field Study Weissová, Kamila Škrabalová, Jitka Skálová, Kateřina Bendová, Zdeňka Kopřivová, Jana J Circadian Rhythms Research Article All Arctic visitors have to deal with extreme conditions, including a constant high light intensity during the summer season or constant darkness during winter. The light/dark cycle serves as the most potent synchronizing signal for the biological clock, and any Arctic visitor attending those regions during winter or summer would struggle with the absence of those entraining signals. However, the inner clock can be synchronized by other zeitgebers such as physical activity, food intake, or social interactions. Here, we investigated the effect of the polar day on the circadian clock of 10 researchers attending the polar base station in the Svalbard region during the summer season. The data collected in Svalbard was compared with data obtained just before leaving for the expedition (in the Czech Republic 49.8175°N, 15.4730°E). To determine the circadian functions, we monitored activity/rest rhythm with wrist actigraphy followed by sleep diaries, melatonin rhythm in saliva, and clock gene expression (Per1, Bmal1, and Nr1D1) in buccal mucosa samples. Our data shows that the two-week stay in Svalbard delayed melatonin onset but did not affect its rhythmic secretion, and delayed the activity/rest rhythm. Furthermore, the clock gene expression displayed a higher amplitude in Svalbard compared to the amplitude detected in the Czech Republic. We hypothesize that the common daily schedule at the Svalbard expedition strengthens circadian rhythmicity even in conditions of compromised light/dark cycles. To our knowledge, this is the first study to demonstrate peripheral clock gene expression during a polar expedition. Ubiquity Press 2019-10-09 /pmc/articles/PMC6788356/ /pubmed/31656532 http://dx.doi.org/10.5334/jcr.186 Text en Copyright: © 2019 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC-BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See http://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Weissová, Kamila
Škrabalová, Jitka
Skálová, Kateřina
Bendová, Zdeňka
Kopřivová, Jana
The Effect of a Common Daily Schedule on Human Circadian Rhythms During the Polar Day in Svalbard: A Field Study
title The Effect of a Common Daily Schedule on Human Circadian Rhythms During the Polar Day in Svalbard: A Field Study
title_full The Effect of a Common Daily Schedule on Human Circadian Rhythms During the Polar Day in Svalbard: A Field Study
title_fullStr The Effect of a Common Daily Schedule on Human Circadian Rhythms During the Polar Day in Svalbard: A Field Study
title_full_unstemmed The Effect of a Common Daily Schedule on Human Circadian Rhythms During the Polar Day in Svalbard: A Field Study
title_short The Effect of a Common Daily Schedule on Human Circadian Rhythms During the Polar Day in Svalbard: A Field Study
title_sort effect of a common daily schedule on human circadian rhythms during the polar day in svalbard: a field study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788356/
https://www.ncbi.nlm.nih.gov/pubmed/31656532
http://dx.doi.org/10.5334/jcr.186
work_keys_str_mv AT weissovakamila theeffectofacommondailyscheduleonhumancircadianrhythmsduringthepolardayinsvalbardafieldstudy
AT skrabalovajitka theeffectofacommondailyscheduleonhumancircadianrhythmsduringthepolardayinsvalbardafieldstudy
AT skalovakaterina theeffectofacommondailyscheduleonhumancircadianrhythmsduringthepolardayinsvalbardafieldstudy
AT bendovazdenka theeffectofacommondailyscheduleonhumancircadianrhythmsduringthepolardayinsvalbardafieldstudy
AT koprivovajana theeffectofacommondailyscheduleonhumancircadianrhythmsduringthepolardayinsvalbardafieldstudy
AT weissovakamila effectofacommondailyscheduleonhumancircadianrhythmsduringthepolardayinsvalbardafieldstudy
AT skrabalovajitka effectofacommondailyscheduleonhumancircadianrhythmsduringthepolardayinsvalbardafieldstudy
AT skalovakaterina effectofacommondailyscheduleonhumancircadianrhythmsduringthepolardayinsvalbardafieldstudy
AT bendovazdenka effectofacommondailyscheduleonhumancircadianrhythmsduringthepolardayinsvalbardafieldstudy
AT koprivovajana effectofacommondailyscheduleonhumancircadianrhythmsduringthepolardayinsvalbardafieldstudy