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The Metabolic Profile of Tumor and Virally Infected Cells Shapes Their Microenvironment Counteracting T Cell Immunity

Upon activation naïve T cells undergo metabolic changes to support the differentiation into subsets of effector or regulatory cells, and enable subsequent metabolic adaptations to form memory. Interfering with these metabolic alterations leads to abrogation or reprogramming of T cell differentiation...

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Detalles Bibliográficos
Autores principales: Magalhaes, Isabelle, Yogev, Ohad, Mattsson, Jonas, Schurich, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788393/
https://www.ncbi.nlm.nih.gov/pubmed/31636636
http://dx.doi.org/10.3389/fimmu.2019.02309