On measuring selection in cancer from subclonal mutation frequencies

Recently available cancer sequencing data have revealed a complex view of the cancer genome containing a multitude of mutations, including drivers responsible for cancer progression and neutral passengers. Measuring selection in cancer and distinguishing drivers from passengers have important implic...

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Detalles Bibliográficos
Autores principales: Bozic, Ivana, Paterson, Chay, Waclaw, Bartlomiej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788714/
https://www.ncbi.nlm.nih.gov/pubmed/31557163
http://dx.doi.org/10.1371/journal.pcbi.1007368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788714/
https://www.ncbi.nlm.nih.gov/pubmed/31557163
http://dx.doi.org/10.1371/journal.pcbi.1007368

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