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On measuring selection in cancer from subclonal mutation frequencies
Recently available cancer sequencing data have revealed a complex view of the cancer genome containing a multitude of mutations, including drivers responsible for cancer progression and neutral passengers. Measuring selection in cancer and distinguishing drivers from passengers have important implic...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788714/ https://www.ncbi.nlm.nih.gov/pubmed/31557163 http://dx.doi.org/10.1371/journal.pcbi.1007368 |