Androgen-regulated transcription of ESRP2 drives alternative splicing patterns in prostate cancer

Prostate is the most frequent cancer in men. Prostate cancer progression is driven by androgen steroid hormones, and delayed by androgen deprivation therapy (ADT). Androgens control transcription by stimulating androgen receptor (AR) activity, yet also control pre-mRNA splicing through less clear me...

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Detalles Bibliográficos
Autores principales: Munkley, Jennifer, Li, Ling, Krishnan, S R Gokul, Hysenaj, Gerald, Scott, Emma, Dalgliesh, Caroline, Oo, Htoo Zarni, Maia, Teresa Mendes, Cheung, Kathleen, Ehrmann, Ingrid, Livermore, Karen E, Zielinska, Hanna, Thompson, Oliver, Knight, Bridget, McCullagh, Paul, McGrath, John, Crundwell, Malcolm, Harries, Lorna W, Daugaard, Mads, Cockell, Simon, Barbosa-Morais, Nuno L, Oltean, Sebastian, Elliott, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788855/
https://www.ncbi.nlm.nih.gov/pubmed/31478829
http://dx.doi.org/10.7554/eLife.47678

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