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Natural Tr1-like cells do not confer long-term tolerogenic memory

IL-10-producing Tr1 cells promote tolerance but their contributions to tolerogenic memory are unclear. Using 10BiT mice that carry a Foxp3-eGFP reporter and stably express CD90.1 following IL-10 production, we characterized the spatiotemporal dynamics of Tr1 cells in a house dust mite model of aller...

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Detalles Bibliográficos
Autores principales:	Yadava, Koshika, Medina, Carlos Obed, Ishak, Heather, Gurevich, Irina, Kuipers, Hedwich, Shamskhou, Elya Ali, Koliesnik, Ievgen O, Moon, James J, Weaver, Casey, Nadeau, Kari Christine, Bollyky, Paul L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788856/ https://www.ncbi.nlm.nih.gov/pubmed/31603425 http://dx.doi.org/10.7554/eLife.44821

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