Brain lateralization probed by water diffusion at the atomic to micrometric scale

Combined neutron scattering and diffusion nuclear magnetic resonance experiments have been used to reveal significant interregional asymmetries (lateralization) in bovine brain hemispheres in terms of myelin arrangement and water dynamics at micron to atomic scales. Thicker myelin sheaths were found...

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Autores principales: Natali, F., Dolce, C., Peters, J., Stelletta, C., Demé, B., Ollivier, J., Leduc, G., Cupane, A., Barbier, E. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789030/
https://www.ncbi.nlm.nih.gov/pubmed/31604980
http://dx.doi.org/10.1038/s41598-019-51022-1
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author Natali, F.
Dolce, C.
Peters, J.
Stelletta, C.
Demé, B.
Ollivier, J.
Leduc, G.
Cupane, A.
Barbier, E. L.
author_facet Natali, F.
Dolce, C.
Peters, J.
Stelletta, C.
Demé, B.
Ollivier, J.
Leduc, G.
Cupane, A.
Barbier, E. L.
author_sort Natali, F.
collection PubMed
description Combined neutron scattering and diffusion nuclear magnetic resonance experiments have been used to reveal significant interregional asymmetries (lateralization) in bovine brain hemispheres in terms of myelin arrangement and water dynamics at micron to atomic scales. Thicker myelin sheaths were found in the left hemisphere using neutron diffraction. 4.7 T dMRI and quasi-elastic neutron experiments highlighted significant differences in the properties of water dynamics in the two hemispheres. The results were interpreted in terms of hemisphere-dependent cellular composition (number of neurons, cell distribution, etc.) as well as specificity of neurological functions (such as preferential networking).
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spelling pubmed-67890302019-10-17 Brain lateralization probed by water diffusion at the atomic to micrometric scale Natali, F. Dolce, C. Peters, J. Stelletta, C. Demé, B. Ollivier, J. Leduc, G. Cupane, A. Barbier, E. L. Sci Rep Article Combined neutron scattering and diffusion nuclear magnetic resonance experiments have been used to reveal significant interregional asymmetries (lateralization) in bovine brain hemispheres in terms of myelin arrangement and water dynamics at micron to atomic scales. Thicker myelin sheaths were found in the left hemisphere using neutron diffraction. 4.7 T dMRI and quasi-elastic neutron experiments highlighted significant differences in the properties of water dynamics in the two hemispheres. The results were interpreted in terms of hemisphere-dependent cellular composition (number of neurons, cell distribution, etc.) as well as specificity of neurological functions (such as preferential networking). Nature Publishing Group UK 2019-10-11 /pmc/articles/PMC6789030/ /pubmed/31604980 http://dx.doi.org/10.1038/s41598-019-51022-1 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Natali, F.
Dolce, C.
Peters, J.
Stelletta, C.
Demé, B.
Ollivier, J.
Leduc, G.
Cupane, A.
Barbier, E. L.
Brain lateralization probed by water diffusion at the atomic to micrometric scale
title Brain lateralization probed by water diffusion at the atomic to micrometric scale
title_full Brain lateralization probed by water diffusion at the atomic to micrometric scale
title_fullStr Brain lateralization probed by water diffusion at the atomic to micrometric scale
title_full_unstemmed Brain lateralization probed by water diffusion at the atomic to micrometric scale
title_short Brain lateralization probed by water diffusion at the atomic to micrometric scale
title_sort brain lateralization probed by water diffusion at the atomic to micrometric scale
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789030/
https://www.ncbi.nlm.nih.gov/pubmed/31604980
http://dx.doi.org/10.1038/s41598-019-51022-1
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