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The C-terminal region of human plasma fetuin-B is dispensable for the raised-elephant-trunk mechanism of inhibition of astacin metallopeptidases
Human fetuin-B plays a key physiological role in human fertility through its inhibitory action on ovastacin, a member of the astacin family of metallopeptidases. The inhibitor consists of tandem cystatin-like domains (CY1 and CY2), which are connected by a linker containing a “CPDCP-trunk” and follo...
Autores principales: | Guevara, Tibisay, Körschgen, Hagen, Cuppari, Anna, Schmitz, Carlo, Kuske, Michael, Yiallouros, Irene, Floehr, Julia, Jahnen-Dechent, Willi, Stöcker, Walter, Gomis-Rüth, F. Xavier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789097/ https://www.ncbi.nlm.nih.gov/pubmed/31604990 http://dx.doi.org/10.1038/s41598-019-51095-y |
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