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The C-terminal region of human plasma fetuin-B is dispensable for the raised-elephant-trunk mechanism of inhibition of astacin metallopeptidases

Human fetuin-B plays a key physiological role in human fertility through its inhibitory action on ovastacin, a member of the astacin family of metallopeptidases. The inhibitor consists of tandem cystatin-like domains (CY1 and CY2), which are connected by a linker containing a “CPDCP-trunk” and follo...

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Detalles Bibliográficos
Autores principales: Guevara, Tibisay, Körschgen, Hagen, Cuppari, Anna, Schmitz, Carlo, Kuske, Michael, Yiallouros, Irene, Floehr, Julia, Jahnen-Dechent, Willi, Stöcker, Walter, Gomis-Rüth, F. Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789097/
https://www.ncbi.nlm.nih.gov/pubmed/31604990
http://dx.doi.org/10.1038/s41598-019-51095-y

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