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Alpha-synuclein stepwise aggregation reveals features of an early onset mutation in Parkinson’s disease
Amyloid formation is a process involving interconverting protein species and results in toxic oligomers and fibrils. Aggregated alpha-synuclein (αS) participates in neurodegenerative maladies, but a closer understanding of the early αS polymerization stages and polymorphism of heritable αS variants...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789109/ https://www.ncbi.nlm.nih.gov/pubmed/31633065 http://dx.doi.org/10.1038/s42003-019-0598-9 |