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Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator
Synthetic gene oscillators have the potential to control timed functions and periodic gene expression in engineered cells. Such oscillators have been refined in bacteria in vitro, however, these systems have lacked the robustness and precision necessary for applications in complex in vivo environmen...
Autores principales: | Riglar, David T., Richmond, David L., Potvin-Trottier, Laurent, Verdegaal, Andrew A., Naydich, Alexander D., Bakshi, Somenath, Leoncini, Emanuele, Lyon, Lorena G., Paulsson, Johan, Silver, Pamela A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789134/ https://www.ncbi.nlm.nih.gov/pubmed/31604953 http://dx.doi.org/10.1038/s41467-019-12638-z |
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