Immunological Assays used to Support Efficacy of Zika Virus Vaccines

In February of 2016, the World Health Organization (WHO) declared Zika virus (ZIKV) a Public Health Emergency of International Concern. This prompted a rapid response from both the private and public sector resulting in the generation of several promising vaccine candidates. In this review, we discu...

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Autores principales: Eckels, Kenneth H., De La Barrera, Rafael A., Putnak, Joseph Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789453/
https://www.ncbi.nlm.nih.gov/pubmed/31261617
http://dx.doi.org/10.3390/tropicalmed4030097
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author Eckels, Kenneth H.
De La Barrera, Rafael A.
Putnak, Joseph Robert
author_facet Eckels, Kenneth H.
De La Barrera, Rafael A.
Putnak, Joseph Robert
author_sort Eckels, Kenneth H.
collection PubMed
description In February of 2016, the World Health Organization (WHO) declared Zika virus (ZIKV) a Public Health Emergency of International Concern. This prompted a rapid response from both the private and public sector resulting in the generation of several promising vaccine candidates. In this review, we discuss published scientific efforts associated with these novel vaccines, emphasizing the immunological assays used to evaluate their immunogenicity and efficacy, and support future licensure.
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spelling pubmed-67894532019-10-16 Immunological Assays used to Support Efficacy of Zika Virus Vaccines Eckels, Kenneth H. De La Barrera, Rafael A. Putnak, Joseph Robert Trop Med Infect Dis Review In February of 2016, the World Health Organization (WHO) declared Zika virus (ZIKV) a Public Health Emergency of International Concern. This prompted a rapid response from both the private and public sector resulting in the generation of several promising vaccine candidates. In this review, we discuss published scientific efforts associated with these novel vaccines, emphasizing the immunological assays used to evaluate their immunogenicity and efficacy, and support future licensure. MDPI 2019-06-28 /pmc/articles/PMC6789453/ /pubmed/31261617 http://dx.doi.org/10.3390/tropicalmed4030097 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Eckels, Kenneth H.
De La Barrera, Rafael A.
Putnak, Joseph Robert
Immunological Assays used to Support Efficacy of Zika Virus Vaccines
title Immunological Assays used to Support Efficacy of Zika Virus Vaccines
title_full Immunological Assays used to Support Efficacy of Zika Virus Vaccines
title_fullStr Immunological Assays used to Support Efficacy of Zika Virus Vaccines
title_full_unstemmed Immunological Assays used to Support Efficacy of Zika Virus Vaccines
title_short Immunological Assays used to Support Efficacy of Zika Virus Vaccines
title_sort immunological assays used to support efficacy of zika virus vaccines
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789453/
https://www.ncbi.nlm.nih.gov/pubmed/31261617
http://dx.doi.org/10.3390/tropicalmed4030097
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