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(+)-Spectaline and Iso-6-Spectaline Induce a Possible Cross-Talk between Autophagy and Apoptosis in Trypanosoma brucei rhodesiense

In our previous study, two known piperidine alkaloids (+)-spectaline (1) and iso-6-spectaline (2) were isolated from the leaves of Senna spectabilis and showed no toxic effect on L6 cells. In view of the potential use of piperidine alkaloids in S. spectabilis for the treatment of sleeping sickness,...

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Detalles Bibliográficos
Autores principales: Lim, Kah Tee, Yeoh, Chiann Ying, Zainuddin, Zafarina, Ilham Adenan, Mohd.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789500/
https://www.ncbi.nlm.nih.gov/pubmed/31266222
http://dx.doi.org/10.3390/tropicalmed4030098