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Determination of Risk Factors for Venous Thromboembolism by an Adapted Caprini Scoring System in Surgical Patients

Venous thromboembolism (VTE) is a frequent preventable complication among surgical patients. Precise risk assessment is a necessary step for providing appropriate thromboprophylaxis and reducing mortality as well as morbidity caused by VTE. We carried out this work to define the rate of VTE postoper...

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Autores principales: Hanh, Bui My, Cuong, Le Quang, Son, Nguyen Truong, Duc, Duong Tuan, Hung, Tran Tien, Hung, Duong Duc, Giang, Tran Binh, Hiep, Nguyen Hoang, Xuyen, Hoang Thi Hong, Nga, Nguyen Thi, Chu, Dinh-Toi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789529/
https://www.ncbi.nlm.nih.gov/pubmed/31319527
http://dx.doi.org/10.3390/jpm9030036
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author Hanh, Bui My
Cuong, Le Quang
Son, Nguyen Truong
Duc, Duong Tuan
Hung, Tran Tien
Hung, Duong Duc
Giang, Tran Binh
Hiep, Nguyen Hoang
Xuyen, Hoang Thi Hong
Nga, Nguyen Thi
Chu, Dinh-Toi
author_facet Hanh, Bui My
Cuong, Le Quang
Son, Nguyen Truong
Duc, Duong Tuan
Hung, Tran Tien
Hung, Duong Duc
Giang, Tran Binh
Hiep, Nguyen Hoang
Xuyen, Hoang Thi Hong
Nga, Nguyen Thi
Chu, Dinh-Toi
author_sort Hanh, Bui My
collection PubMed
description Venous thromboembolism (VTE) is a frequent preventable complication among surgical patients. Precise risk assessment is a necessary step for providing appropriate thromboprophylaxis and reducing mortality as well as morbidity caused by VTE. We carried out this work to define the rate of VTE postoperatively, following a Caprini score, and to determine VTE risk factors through a modified Caprini risk scoring system. This multicenter, observational, cohort study involved 2,790,027 patients who underwent surgery in four Vietnamese hospitals from 01/2017 to 12/2018. All patients who were evaluated before surgery by using a Caprini risk assessment model (RAM) and monitored within 90 days after surgery. The endpoint of the study was ultrasound-confirmed VTE. Our data showed that the 90-day postoperative VTE was found in 3068 patients. Most of VTE (46.97%) cases were found in the highest risk group (Caprini score > 5). A total of 37.19% were observed in the high risk group, while the rest (15.84%) were from low to moderate risk groups. The likelihood of occurring VTE was heightened 2.83 times for patients with a Caprini score of 3–4, 4.83 times for a Caprini score of 5–6, 8.84 times for a score of 7–8, and 11.42 times for a score of >8, comparing to ones with a score of 0 to 2 (all p values < 0.05). Thus, the frequency of postoperative VTE rises substantially, according to the advanced Caprini score. Further categorizing patients among the highest risk group need delivering more appropriate thromboprophylaxis.
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spelling pubmed-67895292019-10-16 Determination of Risk Factors for Venous Thromboembolism by an Adapted Caprini Scoring System in Surgical Patients Hanh, Bui My Cuong, Le Quang Son, Nguyen Truong Duc, Duong Tuan Hung, Tran Tien Hung, Duong Duc Giang, Tran Binh Hiep, Nguyen Hoang Xuyen, Hoang Thi Hong Nga, Nguyen Thi Chu, Dinh-Toi J Pers Med Article Venous thromboembolism (VTE) is a frequent preventable complication among surgical patients. Precise risk assessment is a necessary step for providing appropriate thromboprophylaxis and reducing mortality as well as morbidity caused by VTE. We carried out this work to define the rate of VTE postoperatively, following a Caprini score, and to determine VTE risk factors through a modified Caprini risk scoring system. This multicenter, observational, cohort study involved 2,790,027 patients who underwent surgery in four Vietnamese hospitals from 01/2017 to 12/2018. All patients who were evaluated before surgery by using a Caprini risk assessment model (RAM) and monitored within 90 days after surgery. The endpoint of the study was ultrasound-confirmed VTE. Our data showed that the 90-day postoperative VTE was found in 3068 patients. Most of VTE (46.97%) cases were found in the highest risk group (Caprini score > 5). A total of 37.19% were observed in the high risk group, while the rest (15.84%) were from low to moderate risk groups. The likelihood of occurring VTE was heightened 2.83 times for patients with a Caprini score of 3–4, 4.83 times for a Caprini score of 5–6, 8.84 times for a score of 7–8, and 11.42 times for a score of >8, comparing to ones with a score of 0 to 2 (all p values < 0.05). Thus, the frequency of postoperative VTE rises substantially, according to the advanced Caprini score. Further categorizing patients among the highest risk group need delivering more appropriate thromboprophylaxis. MDPI 2019-07-17 /pmc/articles/PMC6789529/ /pubmed/31319527 http://dx.doi.org/10.3390/jpm9030036 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hanh, Bui My
Cuong, Le Quang
Son, Nguyen Truong
Duc, Duong Tuan
Hung, Tran Tien
Hung, Duong Duc
Giang, Tran Binh
Hiep, Nguyen Hoang
Xuyen, Hoang Thi Hong
Nga, Nguyen Thi
Chu, Dinh-Toi
Determination of Risk Factors for Venous Thromboembolism by an Adapted Caprini Scoring System in Surgical Patients
title Determination of Risk Factors for Venous Thromboembolism by an Adapted Caprini Scoring System in Surgical Patients
title_full Determination of Risk Factors for Venous Thromboembolism by an Adapted Caprini Scoring System in Surgical Patients
title_fullStr Determination of Risk Factors for Venous Thromboembolism by an Adapted Caprini Scoring System in Surgical Patients
title_full_unstemmed Determination of Risk Factors for Venous Thromboembolism by an Adapted Caprini Scoring System in Surgical Patients
title_short Determination of Risk Factors for Venous Thromboembolism by an Adapted Caprini Scoring System in Surgical Patients
title_sort determination of risk factors for venous thromboembolism by an adapted caprini scoring system in surgical patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789529/
https://www.ncbi.nlm.nih.gov/pubmed/31319527
http://dx.doi.org/10.3390/jpm9030036
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