Cargando…

Cellular Mechanisms for Antinociception Produced by Oxytocin and Orexins in the Rat Spinal Lamina II—Comparison with Those of Other Endogenous Pain Modulators

Much evidence indicates that hypothalamus-derived neuropeptides, oxytocin, orexins A and B, inhibit nociceptive transmission in the rat spinal dorsal horn. In order to unveil cellular mechanisms for this antinociception, the effects of the neuropeptides on synaptic transmission were examined in spin...

Descripción completa

Detalles Bibliográficos
Autor principal:	Kumamoto, Eiichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789548/ https://www.ncbi.nlm.nih.gov/pubmed/31527474 http://dx.doi.org/10.3390/ph12030136

Ejemplares similares

Antinociceptive action of oxytocin involves inhibition of potassium channel currents in lamina II neurons of the rat spinal cord
por: Breton, Jean Didier, et al.
Publicado: (2009)

Oxytocin-induced antinociception in the spinal cord is mediated by a subpopulation of glutamatergic neurons in lamina I-II which amplify GABAergic inhibition
por: Breton, Jean-Didier, et al.
Publicado: (2008)

Developmental change and sexual difference in synaptic modulation produced by oxytocin in rat substantia gelatinosa neurons
por: Jiang, Chang-Yu, et al.
Publicado: (2016)

A putative relay circuit providing low-threshold mechanoreceptive input to lamina I projection neurons via vertical cells in lamina II of the rat dorsal horn
por: Yasaka, Toshiharu, et al.
Publicado: (2014)

Antinociceptive effect of intermittent fasting via the orexin pathway on formalin-induced acute pain in mice
por: Shin, Hyunjin, et al.
Publicado: (2023)

Oxytocin-Trust Link in Oxytocin-Sensitive Participants and Those Without Autistic Traits
por: Kurokawa, Hirofumi, et al.
Publicado: (2021)

Inhibition of Fast Nerve Conduction Produced by Analgesics and Analgesic Adjuvants—Possible Involvement in Pain Alleviation
por: Kumamoto, Eiichi
Publicado: (2020)

Involvement of central opiate receptors in modulation of centrally administered oxytocin-induced antinociception
por: Erfanparast, Amir, et al.
Publicado: (2018)

Oxytocin and orexin systems bidirectionally regulate the ability of opioid cues to bias reward seeking
por: Giannotti, Giuseppe, et al.
Publicado: (2022)

Administration of orexin receptor 1 antagonist into the rostral ventromedial medulla increased swim stress-induced antinociception in rat
por: Soliemani, Neda, et al.
Publicado: (2016)

Lamina‐specific properties of spinal astrocytes
por: Kronschläger, Mira T., et al.
Publicado: (2021)

Spinal gabapentin and antinociception: mechanisms of action.
por: Yoon, Myung Ha, et al.
Publicado: (2003)

Intra-accumbal Orexin-1 Receptors are Involved in Antinociception Induced by Stimulation of the Lateral Hypothalamus in the Formalin Test as an Animal Model of Persistent Inflammatory Pain
por: Jahangirvand, Mahboubeh, et al.
Publicado: (2016)

Intranasal neuropeptide Y is most effective in some aspects of acute stress compared to melatonin, oxytocin and orexin
por: Zubkov, Eugene, et al.
Publicado: (2022)

Intranasal Administration for Pain: Oxytocin and Other Polypeptides
por: Bharadwaj, Vimala N., et al.
Publicado: (2021)

β-arrestin-2 regulates NMDA receptor function in spinal lamina II neurons and duration of persistent pain
por: Chen, Gang, et al.
Publicado: (2016)

Endogenous Oxytocin, Vasopressin, and Aggression in Domestic Dogs
por: MacLean, Evan L., et al.
Publicado: (2017)

Effects of Various Antiepileptics Used to Alleviate Neuropathic Pain on Compound Action Potential in Frog Sciatic Nerves: Comparison with Those of Local Anesthetics
por: Uemura, Yuhei, et al.
Publicado: (2014)

Electroacupuncture at 2/100 Hz Activates Antinociceptive Spinal Mechanisms Different from Those Activated by Electroacupuncture at 2 and 100 Hz in Responder Rats
por: da Silva, Josie Resende Torres, et al.
Publicado: (2013)

The Endogenous Opioids Related with Antinociceptive Effects Induced by Electrical Stimulation into the Amygdala
por: Nakamura, Takami, et al.
Publicado: (2013)

Curcumin Exerts Antinociceptive Effects in Cancer-Induced Bone Pain via an Endogenous Opioid Mechanism
por: Zhao, Guanghai, et al.
Publicado: (2021)

Endogenous oxytocin levels in children with autism: Associations with cortisol levels and oxytocin receptor gene methylation
por: Evenepoel, Margaux, et al.
Publicado: (2023)

Assessment of Mechanisms Involved in Antinociception Produced by the Alkaloid Caulerpine
por: Cavalcante-Silva, Luiz Henrique Agra, et al.
Publicado: (2014)

Progesterone Application to the Rat Forehead Produces Corneal Antinociception
por: Meng, Ian D., et al.
Publicado: (2019)

Systemic and intrathecal baclofen produce bladder antinociception in rats
por: Ness, Timothy J., et al.
Publicado: (2021)

Endogenous Oxytocin Levels in Autism—A Meta-Analysis
por: Moerkerke, Matthijs, et al.
Publicado: (2021)

Endogenous oxytocin, cortisol, and testosterone in response to group singing
por: Bowling, D.L., et al.
Publicado: (2022)

Differential regulation of morphine antinociceptive effects by endogenous enkephalinergic system in the forebrain of mice
por: Chen, Tsung-Chieh, et al.
Publicado: (2008)

Cell-Type Specific Distribution of T-Type Calcium Currents in Lamina II Neurons of the Rat Spinal Cord
por: Wu, Jing, et al.
Publicado: (2018)

Differential Activation of TRP Channels in the Adult Rat Spinal Substantia Gelatinosa by Stereoisomers of Plant-Derived Chemicals
por: Kumamoto, Eiichi, et al.
Publicado: (2016)

Functional cardiac orexin receptors: role of orexin-B/orexin 2 receptor in myocardial protection
por: Patel, Vanlata H., et al.
Publicado: (2018)

Orexin, orexin receptor antagonists and central cardiovascular control
por: Carrive, Pascal
Publicado: (2013)

Melatonin MT2 receptor agonist IIK-7 produces antinociception by modulation of ROS and suppression of spinal microglial activation in neuropathic pain rats
por: Kuthati, Yaswanth, et al.
Publicado: (2019)

Involvement of spinal orexin A in the electroacupuncture analgesia in a rat model of post-laparotomy pain
por: Feng, Xiao-Ming, et al.
Publicado: (2012)

The role of spinal adrenergic receptors on the antinociception of ginsenosides in a rat postoperative pain model
por: Kim, In Ji, et al.
Publicado: (2013)

Hop Extract Produces Antinociception by Acting on Opioid System in Mice
por: Park, Soo-Hyun, et al.
Publicado: (2012)

The antinociception of oxytocin on colonic hypersensitivity in rats was mediated by inhibition of mast cell degranulation via Ca(2+)-NOS pathway
por: Gong, Liping, et al.
Publicado: (2016)

Dissociating orexin-dependent and -independent functions of orexin neurons using novel Orexin-Flp knock-in mice
por: Chowdhury, Srikanta, et al.
Publicado: (2019)

Potential of Endogenous Oxytocin in Endocrine Treatment and Prevention of COVID-19
por: Wang, Stephani C., et al.
Publicado: (2022)

Spinal orexin A attenuates opioid-induced mechanical hypersensitivity in the rat
por: Youn, Dong-ho, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_473lqttplit187bfh9opr8dq5r