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Sequential Immunization with Universal Live Attenuated Influenza Vaccine Candidates Protects Ferrets against a High-Dose Heterologous Virus Challenge
The development of universal influenza vaccines has been a priority for more than 20 years. We conducted a preclinical study in ferrets of two sets of live attenuated influenza vaccines (LAIVs) expressing chimeric hemagglutinin (cHA). These vaccines contained the HA stalk domain from H1N1pdm09 virus...
Autores principales: | Isakova-Sivak, Irina, Matyushenko, Victoria, Kotomina, Tatiana, Kiseleva, Irina, Krutikova, Elena, Donina, Svetlana, Rekstin, Andrey, Larionova, Natalia, Mezhenskaya, Daria, Sivak, Konstantin, Muzhikyan, Arman, Katelnikova, Anastasia, Rudenko, Larisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789596/ https://www.ncbi.nlm.nih.gov/pubmed/31288422 http://dx.doi.org/10.3390/vaccines7030061 |
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