RNA ligation precedes the retrotransposition of U6/LINE-1 chimeric RNA

Long interspersed element-1 (LINE-1 or L1) amplifies via retrotransposition. Active L1s encode 2 proteins (ORF1p and ORF2p) that bind their encoding transcript to promote retrotransposition in cis. The L1-encoded proteins also promote the retrotransposition of small-interspersed element RNAs, noncod...

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Detalles Bibliográficos
Autores principales: Moldovan, John B., Wang, Yifan, Shuman, Stewart, Mills, Ryan E., Moran, John V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789731/
https://www.ncbi.nlm.nih.gov/pubmed/31548405
http://dx.doi.org/10.1073/pnas.1805404116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789731/
https://www.ncbi.nlm.nih.gov/pubmed/31548405
http://dx.doi.org/10.1073/pnas.1805404116

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