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Intragenomic variability and extended sequence patterns in the mutational signature of ultraviolet light
Mutational signatures can reveal properties of underlying mutational processes and are important when assessing signals of selection in cancer. Here, we describe the sequence characteristics of mutations induced by ultraviolet (UV) light, a major mutagen in several human cancers, in terms of extende...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789905/ https://www.ncbi.nlm.nih.gov/pubmed/31548379 http://dx.doi.org/10.1073/pnas.1909021116 |