Synthesis and Biological Evaluation of Structurally Varied 5′-/6′-Isonucleosides and Theobromine-Containing N-Isonucleosidyl Derivatives

Isonucleosides are rather stable regioisomeric analogs of nucleosides with broad therapeutic potential. We have previously demonstrated the ability of 5′ and 6′-isonucleosides to inhibit the activity of acetylcholinesterase, a major target for Alzheimer’s disease therapy. Continuing with our researc...

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Detalles Bibliográficos
Autores principales: Xavier, Nuno M., de Sousa, Eduardo C., Pereira, Margarida P., Loesche, Anne, Serbian, Immo, Csuk, René, Oliveira, M. Conceição
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790002/
https://www.ncbi.nlm.nih.gov/pubmed/31269639
http://dx.doi.org/10.3390/ph12030103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790002/
https://www.ncbi.nlm.nih.gov/pubmed/31269639
http://dx.doi.org/10.3390/ph12030103

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