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High-level expression of protein tyrosine phosphatase non-receptor 12 is a strong and independent predictor of poor prognosis in prostate cancer

BACKGROUND: Protein tyrosine phosphatase non-receptor 12 (PTPN12) is ubiquitously tyrosine phosphatase with tumor suppressive properties. METHODS: PTPN12 expression was analyzed by immunohistochemistry on a tissue microarray with 13,660 clinical prostate cancer specimens. RESULTS: PTPN12 staining wa...

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Detalles Bibliográficos
Autores principales:	Weidemann, Sören A., Sauer, Charlotte, Luebke, Andreas M., Möller-Koop, Christina, Steurer, Stefan, Hube-Magg, Claudia, Büscheck, Franziska, Höflmayer, Doris, Tsourlakis, Maria Christina, Clauditz, Till S., Simon, Ronald, Sauter, Guido, Göbel, Cosima, Lebok, Patrick, Dum, David, Fraune, Christoph, Kind, Simon, Minner, Sarah, Izbicki, Jakob, Schlomm, Thorsten, Huland, Hartwig, Heinzer, Hans, Burandt, Eike, Haese, Alexander, Graefen, Markus, Heumann, Asmus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790047/ https://www.ncbi.nlm.nih.gov/pubmed/31606028 http://dx.doi.org/10.1186/s12885-019-6182-3

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