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Modeling post‐translational modifications and cancer‐associated mutations that impact the heterochromatin protein 1α‐importin α heterodimers

Heterochromatin protein 1α (HP1α) is a protein that mediates cancer‐associated processes in the cell nucleus. Proteomic experiments, reported here, demonstrate that HP1α complexes with importin α (IMPα), a protein necessary for its nuclear transport. This data is congruent with Simple Linear Motif (...

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Detalles Bibliográficos
Autores principales:	Zimmermann, Michael T., Williams, Monique M., Klee, Eric W., Lomberk, Gwen A., Urrutia, Raul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790107/ https://www.ncbi.nlm.nih.gov/pubmed/31152607 http://dx.doi.org/10.1002/prot.25752

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