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Modeling post‐translational modifications and cancer‐associated mutations that impact the heterochromatin protein 1α‐importin α heterodimers
Heterochromatin protein 1α (HP1α) is a protein that mediates cancer‐associated processes in the cell nucleus. Proteomic experiments, reported here, demonstrate that HP1α complexes with importin α (IMPα), a protein necessary for its nuclear transport. This data is congruent with Simple Linear Motif (...
Autores principales: | Zimmermann, Michael T., Williams, Monique M., Klee, Eric W., Lomberk, Gwen A., Urrutia, Raul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790107/ https://www.ncbi.nlm.nih.gov/pubmed/31152607 http://dx.doi.org/10.1002/prot.25752 |
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