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MiR-218: A Molecular Switch and Potential Biomarker of Susceptibility to Stress

Low miR-218 expression in the medial prefrontal cortex (mPFC) is a consistent trait of depression. Here we assessed whether miR-218 in the mPFC confers resilience or susceptibility to depression-like behaviors in adult mice, using the chronic social defeat stress (CSDS) model of depression. We also...

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Detalles Bibliográficos
Autores principales: Torres-Berrío, Angélica, Nouel, Dominique, Cuesta, Santiago, Parise, Eric M., Restrepo-Lozano, José María, Larochelle, Pier, Nestler, Eric J., Flores, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790160/
https://www.ncbi.nlm.nih.gov/pubmed/30980043
http://dx.doi.org/10.1038/s41380-019-0421-5