Cargando…

Analysis of macaque BTN3A genes and transcripts in the extended MHC: conserved orthologs of human γδ T cell modulators

Butyrophilins (BTN), specifically BTN3A, play a central role in the modulation of γδ T cells, which are mainly present in gut and mucosal tissues. BTN3A1 is known, for example, to activate Vγ9Vδ2 T cells by means of a phosphoantigen interaction. In the extended HLA region, three genes are located, d...

Descripción completa

Detalles Bibliográficos
Autores principales: de Groot, Nanine, Groen, Rens, Orie, Vaneesha, Bruijnesteijn, Jesse, de Groot, Natasja G., Doxiadis, Gaby G. M., Bontrop, Ronald E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790196/
https://www.ncbi.nlm.nih.gov/pubmed/31384962
http://dx.doi.org/10.1007/s00251-019-01126-9