Ligandomes obtained from different HLA-class II-molecules are homologous for N- and C-terminal residues outside the peptide-binding cleft

Human CD4+ T lymphocytes play an important role in inducing potent immune responses. T cells are activated and stimulated by peptides presented in human leucocyte antigen (HLA)-class II molecules. These HLA-class II molecules typically present peptides of between 12 and 20 amino acids in length. The...

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Detalles Bibliográficos
Autores principales: Kampstra, Arieke S.B., van Heemst, Jurgen, Janssen, George M., de Ru, Arnoud H., van Lummel, Menno, van Veelen, Peter A., Toes, René E.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790208/
https://www.ncbi.nlm.nih.gov/pubmed/31520135
http://dx.doi.org/10.1007/s00251-019-01129-6

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