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METTL3-mediated N6-methyladenosine modification is critical for epithelial-mesenchymal transition and metastasis of gastric cancer

BACKGROUND: As one of the most frequent chemical modifications in eukaryotic mRNAs, N6-methyladenosine (m6A) modification exerts important effects on mRNA stability, splicing, and translation. Recently, the regulatory role of m6A in tumorigenesis has been increasingly recognized. However, dysregulat...

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Detalles Bibliográficos
Autores principales:	Yue, Ben, Song, Chenlong, Yang, Linxi, Cui, Ran, Cheng, Xingwang, Zhang, Zizhen, Zhao, Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790244/ https://www.ncbi.nlm.nih.gov/pubmed/31607270 http://dx.doi.org/10.1186/s12943-019-1065-4

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