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From clinical appearance to accurate management in acute ischemic stroke patients: With the guidance of innovative traditional Chinese medicine diagnosis

OBJECTIVE: To investigate the correlation between simplified classification and laboratory indicators in patients with acute ischemic stroke, also provide accurate evidences for simplified classification and guide clinical interventions and treatment. METHODS: Two hundred patients with acute ischemi...

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Autores principales: Song, Juexian, Xu, Cuiyu, Zhang, Jing, Gao, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790312/
https://www.ncbi.nlm.nih.gov/pubmed/31566916
http://dx.doi.org/10.1002/brb3.1411
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author Song, Juexian
Xu, Cuiyu
Zhang, Jing
Gao, Li
author_facet Song, Juexian
Xu, Cuiyu
Zhang, Jing
Gao, Li
author_sort Song, Juexian
collection PubMed
description OBJECTIVE: To investigate the correlation between simplified classification and laboratory indicators in patients with acute ischemic stroke, also provide accurate evidences for simplified classification and guide clinical interventions and treatment. METHODS: Two hundred patients with acute ischemic stroke were classified into four types according to the characteristics of Traditional Chinese Medicine syndrome: phlegm‐heat syndrome, phlegm‐dampness syndrome, qi deficiency syndrome, and yin deficiency syndrome. The differences between the types of syndromes and the correlation between laboratory indicators and syndromes were analyzed. RESULTS: Among the 200 patients with acute ischemic stroke, there were significant differences in the level of low‐density lipoprotein (LDL‐C) (p < .05) between patients with phlegm‐heat syndrome and other three types. There were significant differences in the levels of homocysteine (HCY) and fibrinogen (Fib) between patients with yin deficiency syndrome and other three types (p < .05). In addition, there were statistically significant differences in blood glucose (Glu), glycosylated hemoglobin (HBA1c), and total cholesterol (CHO) between phlegm‐heat syndrome and qi deficiency syndrome (p < .05). There were significant differences in the levels of Glu, HBA1c, D‐2 polymer (D‐D), and C‐reactive protein (CRP)s between patients with phlegm‐heat syndrome and phlegm‐dampness syndrome (p < .05). There were statistically significant differences in the levels of CRP and urea nitrogen between patients with yin deficiency syndrome and phlegm‐dampness syndrome and qi deficiency syndrome (p < .05). CONCLUSIONS: The four‐type simplified classification of Integrated TCM and Western medicine in acute ischemic stroke has specific laboratory data to support. Simplified classification with TCM treatment and intervention of different patients improves the survival and treatment, which is an innovative, easy‐to‐master clinical diagnosis and treatment model.
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spelling pubmed-67903122019-10-21 From clinical appearance to accurate management in acute ischemic stroke patients: With the guidance of innovative traditional Chinese medicine diagnosis Song, Juexian Xu, Cuiyu Zhang, Jing Gao, Li Brain Behav Original Research OBJECTIVE: To investigate the correlation between simplified classification and laboratory indicators in patients with acute ischemic stroke, also provide accurate evidences for simplified classification and guide clinical interventions and treatment. METHODS: Two hundred patients with acute ischemic stroke were classified into four types according to the characteristics of Traditional Chinese Medicine syndrome: phlegm‐heat syndrome, phlegm‐dampness syndrome, qi deficiency syndrome, and yin deficiency syndrome. The differences between the types of syndromes and the correlation between laboratory indicators and syndromes were analyzed. RESULTS: Among the 200 patients with acute ischemic stroke, there were significant differences in the level of low‐density lipoprotein (LDL‐C) (p < .05) between patients with phlegm‐heat syndrome and other three types. There were significant differences in the levels of homocysteine (HCY) and fibrinogen (Fib) between patients with yin deficiency syndrome and other three types (p < .05). In addition, there were statistically significant differences in blood glucose (Glu), glycosylated hemoglobin (HBA1c), and total cholesterol (CHO) between phlegm‐heat syndrome and qi deficiency syndrome (p < .05). There were significant differences in the levels of Glu, HBA1c, D‐2 polymer (D‐D), and C‐reactive protein (CRP)s between patients with phlegm‐heat syndrome and phlegm‐dampness syndrome (p < .05). There were statistically significant differences in the levels of CRP and urea nitrogen between patients with yin deficiency syndrome and phlegm‐dampness syndrome and qi deficiency syndrome (p < .05). CONCLUSIONS: The four‐type simplified classification of Integrated TCM and Western medicine in acute ischemic stroke has specific laboratory data to support. Simplified classification with TCM treatment and intervention of different patients improves the survival and treatment, which is an innovative, easy‐to‐master clinical diagnosis and treatment model. John Wiley and Sons Inc. 2019-09-30 /pmc/articles/PMC6790312/ /pubmed/31566916 http://dx.doi.org/10.1002/brb3.1411 Text en © 2019 The Authors. Brain and Behavior published by Wiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research
Song, Juexian
Xu, Cuiyu
Zhang, Jing
Gao, Li
From clinical appearance to accurate management in acute ischemic stroke patients: With the guidance of innovative traditional Chinese medicine diagnosis
title From clinical appearance to accurate management in acute ischemic stroke patients: With the guidance of innovative traditional Chinese medicine diagnosis
title_full From clinical appearance to accurate management in acute ischemic stroke patients: With the guidance of innovative traditional Chinese medicine diagnosis
title_fullStr From clinical appearance to accurate management in acute ischemic stroke patients: With the guidance of innovative traditional Chinese medicine diagnosis
title_full_unstemmed From clinical appearance to accurate management in acute ischemic stroke patients: With the guidance of innovative traditional Chinese medicine diagnosis
title_short From clinical appearance to accurate management in acute ischemic stroke patients: With the guidance of innovative traditional Chinese medicine diagnosis
title_sort from clinical appearance to accurate management in acute ischemic stroke patients: with the guidance of innovative traditional chinese medicine diagnosis
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790312/
https://www.ncbi.nlm.nih.gov/pubmed/31566916
http://dx.doi.org/10.1002/brb3.1411
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