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Does sugammadex decrease the severity of agitation and complications in pediatric patients undergoing adenotonsillectomy?
OBJECTIVES: To evaluate the effectiveness of sugammadex in reducing or eliminating postoperative agitation levels, early respiratory complications and nausea/vomiting in children undergoing adenotonsillectomy. METHODS: A total of 70 patients (age range: 5-13 years) who underwent an adenotonsillectom...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Saudi Medical Journal
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790488/ https://www.ncbi.nlm.nih.gov/pubmed/31522218 http://dx.doi.org/10.15537/smj.2019.9.24485 |
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author | Korkmaz, Muge O. Sayhan, Havva Guven, Mehmet |
author_facet | Korkmaz, Muge O. Sayhan, Havva Guven, Mehmet |
author_sort | Korkmaz, Muge O. |
collection | PubMed |
description | OBJECTIVES: To evaluate the effectiveness of sugammadex in reducing or eliminating postoperative agitation levels, early respiratory complications and nausea/vomiting in children undergoing adenotonsillectomy. METHODS: A total of 70 patients (age range: 5-13 years) who underwent an adenotonsillectomy in the Otolaryngology Clinic, Sakarya University, Sakarya, Turkey between May 2015 and September 2017 were included in the study. The patients were randomized into a sugammadex group (Group S) and a neostigmine + atropine (Group N); each group contained 35 patients. Time to extubation, postoperative agitation levels, and early postoperative complications were evaluated and recorded. Data from both groups were statistically evaluated and compared. RESULTS: The time to extubation was significantly shorter in Group S than Group N (p<0.05). Agitation scores during recovery were significantly lower in Group S than Group N (p<0.05). More complications were observed in Group N than in Group S; the number of patients seen coughing and experiencing nausea/vomiting in Group S was statistically significantly lower (p<0.05). CONCLUSION: This study demonstrated that the use of sugammadex results in less time to recovery and less agitation in comparison to conventional administration of neostigmine + atropine in the reversal of neuromuscular blocking after adenotonsillectomy. |
format | Online Article Text |
id | pubmed-6790488 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Saudi Medical Journal |
record_format | MEDLINE/PubMed |
spelling | pubmed-67904882021-02-26 Does sugammadex decrease the severity of agitation and complications in pediatric patients undergoing adenotonsillectomy? Korkmaz, Muge O. Sayhan, Havva Guven, Mehmet Saudi Med J Original Article OBJECTIVES: To evaluate the effectiveness of sugammadex in reducing or eliminating postoperative agitation levels, early respiratory complications and nausea/vomiting in children undergoing adenotonsillectomy. METHODS: A total of 70 patients (age range: 5-13 years) who underwent an adenotonsillectomy in the Otolaryngology Clinic, Sakarya University, Sakarya, Turkey between May 2015 and September 2017 were included in the study. The patients were randomized into a sugammadex group (Group S) and a neostigmine + atropine (Group N); each group contained 35 patients. Time to extubation, postoperative agitation levels, and early postoperative complications were evaluated and recorded. Data from both groups were statistically evaluated and compared. RESULTS: The time to extubation was significantly shorter in Group S than Group N (p<0.05). Agitation scores during recovery were significantly lower in Group S than Group N (p<0.05). More complications were observed in Group N than in Group S; the number of patients seen coughing and experiencing nausea/vomiting in Group S was statistically significantly lower (p<0.05). CONCLUSION: This study demonstrated that the use of sugammadex results in less time to recovery and less agitation in comparison to conventional administration of neostigmine + atropine in the reversal of neuromuscular blocking after adenotonsillectomy. Saudi Medical Journal 2019-09 /pmc/articles/PMC6790488/ /pubmed/31522218 http://dx.doi.org/10.15537/smj.2019.9.24485 Text en Copyright: © Saudi Medical Journal http://creativecommons.org/licenses/by-nc This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial License (CC BY-NC), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Korkmaz, Muge O. Sayhan, Havva Guven, Mehmet Does sugammadex decrease the severity of agitation and complications in pediatric patients undergoing adenotonsillectomy? |
title | Does sugammadex decrease the severity of agitation and complications in pediatric patients undergoing adenotonsillectomy? |
title_full | Does sugammadex decrease the severity of agitation and complications in pediatric patients undergoing adenotonsillectomy? |
title_fullStr | Does sugammadex decrease the severity of agitation and complications in pediatric patients undergoing adenotonsillectomy? |
title_full_unstemmed | Does sugammadex decrease the severity of agitation and complications in pediatric patients undergoing adenotonsillectomy? |
title_short | Does sugammadex decrease the severity of agitation and complications in pediatric patients undergoing adenotonsillectomy? |
title_sort | does sugammadex decrease the severity of agitation and complications in pediatric patients undergoing adenotonsillectomy? |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790488/ https://www.ncbi.nlm.nih.gov/pubmed/31522218 http://dx.doi.org/10.15537/smj.2019.9.24485 |
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