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Does sugammadex decrease the severity of agitation and complications in pediatric patients undergoing adenotonsillectomy?

OBJECTIVES: To evaluate the effectiveness of sugammadex in reducing or eliminating postoperative agitation levels, early respiratory complications and nausea/vomiting in children undergoing adenotonsillectomy. METHODS: A total of 70 patients (age range: 5-13 years) who underwent an adenotonsillectom...

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Autores principales: Korkmaz, Muge O., Sayhan, Havva, Guven, Mehmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Saudi Medical Journal 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790488/
https://www.ncbi.nlm.nih.gov/pubmed/31522218
http://dx.doi.org/10.15537/smj.2019.9.24485
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author Korkmaz, Muge O.
Sayhan, Havva
Guven, Mehmet
author_facet Korkmaz, Muge O.
Sayhan, Havva
Guven, Mehmet
author_sort Korkmaz, Muge O.
collection PubMed
description OBJECTIVES: To evaluate the effectiveness of sugammadex in reducing or eliminating postoperative agitation levels, early respiratory complications and nausea/vomiting in children undergoing adenotonsillectomy. METHODS: A total of 70 patients (age range: 5-13 years) who underwent an adenotonsillectomy in the Otolaryngology Clinic, Sakarya University, Sakarya, Turkey between May 2015 and September 2017 were included in the study. The patients were randomized into a sugammadex group (Group S) and a neostigmine + atropine (Group N); each group contained 35 patients. Time to extubation, postoperative agitation levels, and early postoperative complications were evaluated and recorded. Data from both groups were statistically evaluated and compared. RESULTS: The time to extubation was significantly shorter in Group S than Group N (p<0.05). Agitation scores during recovery were significantly lower in Group S than Group N (p<0.05). More complications were observed in Group N than in Group S; the number of patients seen coughing and experiencing nausea/vomiting in Group S was statistically significantly lower (p<0.05). CONCLUSION: This study demonstrated that the use of sugammadex results in less time to recovery and less agitation in comparison to conventional administration of neostigmine + atropine in the reversal of neuromuscular blocking after adenotonsillectomy.
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spelling pubmed-67904882021-02-26 Does sugammadex decrease the severity of agitation and complications in pediatric patients undergoing adenotonsillectomy? Korkmaz, Muge O. Sayhan, Havva Guven, Mehmet Saudi Med J Original Article OBJECTIVES: To evaluate the effectiveness of sugammadex in reducing or eliminating postoperative agitation levels, early respiratory complications and nausea/vomiting in children undergoing adenotonsillectomy. METHODS: A total of 70 patients (age range: 5-13 years) who underwent an adenotonsillectomy in the Otolaryngology Clinic, Sakarya University, Sakarya, Turkey between May 2015 and September 2017 were included in the study. The patients were randomized into a sugammadex group (Group S) and a neostigmine + atropine (Group N); each group contained 35 patients. Time to extubation, postoperative agitation levels, and early postoperative complications were evaluated and recorded. Data from both groups were statistically evaluated and compared. RESULTS: The time to extubation was significantly shorter in Group S than Group N (p<0.05). Agitation scores during recovery were significantly lower in Group S than Group N (p<0.05). More complications were observed in Group N than in Group S; the number of patients seen coughing and experiencing nausea/vomiting in Group S was statistically significantly lower (p<0.05). CONCLUSION: This study demonstrated that the use of sugammadex results in less time to recovery and less agitation in comparison to conventional administration of neostigmine + atropine in the reversal of neuromuscular blocking after adenotonsillectomy. Saudi Medical Journal 2019-09 /pmc/articles/PMC6790488/ /pubmed/31522218 http://dx.doi.org/10.15537/smj.2019.9.24485 Text en Copyright: © Saudi Medical Journal http://creativecommons.org/licenses/by-nc This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial License (CC BY-NC), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Korkmaz, Muge O.
Sayhan, Havva
Guven, Mehmet
Does sugammadex decrease the severity of agitation and complications in pediatric patients undergoing adenotonsillectomy?
title Does sugammadex decrease the severity of agitation and complications in pediatric patients undergoing adenotonsillectomy?
title_full Does sugammadex decrease the severity of agitation and complications in pediatric patients undergoing adenotonsillectomy?
title_fullStr Does sugammadex decrease the severity of agitation and complications in pediatric patients undergoing adenotonsillectomy?
title_full_unstemmed Does sugammadex decrease the severity of agitation and complications in pediatric patients undergoing adenotonsillectomy?
title_short Does sugammadex decrease the severity of agitation and complications in pediatric patients undergoing adenotonsillectomy?
title_sort does sugammadex decrease the severity of agitation and complications in pediatric patients undergoing adenotonsillectomy?
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790488/
https://www.ncbi.nlm.nih.gov/pubmed/31522218
http://dx.doi.org/10.15537/smj.2019.9.24485
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