Loss of FBXO7 results in a Parkinson's‐like dopaminergic degeneration via an RPL23–MDM2–TP53 pathway

The field of Parkinson's disease research has been impeded by the absence of animal models that clearly phenocopy the features of this neurodegenerative condition. Mutations in FBXO7/PARK15 are associated with both sporadic Parkinson's disease and a severe form of autosomal recessive early...

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Detalles Bibliográficos
Autores principales: Stott, Simon RW, Randle, Suzanne J, Al Rawi, Sara, Rowicka, Paulina A, Harris, Rebecca, Mason, Bethany, Xia, Jing, Dalley, Jeffrey W, Barker, Roger A, Laman, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2019
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790581/
https://www.ncbi.nlm.nih.gov/pubmed/31144295
http://dx.doi.org/10.1002/path.5312

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