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A recurrent clonally distinct Burkitt lymphoma case highlights genetic key events contributing to oncogenesis
Burkitt lymphoma (BL) is characterized by a translocation of the MYC oncogene that leads to the upregulation of MYC expression, cell growth and proliferation. It is well‐established that MYC translocation is not a sufficient genetic event to cause BL. Next‐generation sequencing has recently provided...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790587/ https://www.ncbi.nlm.nih.gov/pubmed/30779244 http://dx.doi.org/10.1002/gcc.22743 |