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Epidemiology of chronic kidney disease in Australian general practice: National Prescribing Service MedicineWise MedicineInsight dataset

AIM: To describe sociodemographic characteristics and comorbidities of a large cohort of Australian general practice‐based patients identified as having chronic kidney disease (CKD), using data from National Prescribing Service (NPS) MedicineWise's MedicineInsight dataset, and compare this data...

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Autores principales: Radford, Janette, Kitsos, Alex, Stankovich, Jim, Castelino, Ronald, Khanam, Masuma, Jose, Matthew, Peterson, Gregory, Saunder, Timothy, Wimmer, Barbara, Razizaidi, Tabish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790712/
https://www.ncbi.nlm.nih.gov/pubmed/30467996
http://dx.doi.org/10.1111/nep.13537
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author Radford, Janette
Kitsos, Alex
Stankovich, Jim
Castelino, Ronald
Khanam, Masuma
Jose, Matthew
Peterson, Gregory
Saunder, Timothy
Wimmer, Barbara
Razizaidi, Tabish
author_facet Radford, Janette
Kitsos, Alex
Stankovich, Jim
Castelino, Ronald
Khanam, Masuma
Jose, Matthew
Peterson, Gregory
Saunder, Timothy
Wimmer, Barbara
Razizaidi, Tabish
author_sort Radford, Janette
collection PubMed
description AIM: To describe sociodemographic characteristics and comorbidities of a large cohort of Australian general practice‐based patients identified as having chronic kidney disease (CKD), using data from National Prescribing Service (NPS) MedicineWise's MedicineInsight dataset, and compare this dataset to the 2011–2012 Australian Health Survey's (AHS) CKD prevalence estimates. METHODS: This was a cohort study using deidentified, longitudinal, electronic health record data collected from 329 practices and 1 483 416 patients distributed across Australia, from 1 June 2013 until 1 June 2016. Two methods were used to calculate the CKD prevalence. One used the same method as used by the 2011–2012 AHS, based on one estimate of the estimated glomerular filtration rate (eGFR) or albumin/creatinine ratios (ACR). The other defined CKD more rigorously using eGFR or ACR results at least 90 days apart. RESULTS: In 2016, of 1 310 602 active patients, 710 674 (54.2%) did not have an eGFR or ACR test, while 524 961 (40.1%) had an eGFR or ACR test but did not meet AHS criteria for CKD. Age–sex adjusted rates of CKD (compared to AHS) were CKD 1–0.45% (3.9%), CKD 2–0.62% (2.5%), CKD 3a: 3.1% (2.7%), CKD 3b: 1.14% (0.6%), CKD 4–5: 0.41% (0.3%). The CKD cohort defined more rigorously using eGFR and ACR measures >90 days apart, had comorbidities of atrial fibrillation (30.5%), cardiovascular disease (25.0%), diabetes mellitus (17.1%) and hypertension (14.8%). CONCLUSION: The MedicineInsight dataset contains valuable and timely information about Australian patients with CKD, and provides prevalence estimates similar to those from AHS data.
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spelling pubmed-67907122019-10-21 Epidemiology of chronic kidney disease in Australian general practice: National Prescribing Service MedicineWise MedicineInsight dataset Radford, Janette Kitsos, Alex Stankovich, Jim Castelino, Ronald Khanam, Masuma Jose, Matthew Peterson, Gregory Saunder, Timothy Wimmer, Barbara Razizaidi, Tabish Nephrology (Carlton) Original Articles AIM: To describe sociodemographic characteristics and comorbidities of a large cohort of Australian general practice‐based patients identified as having chronic kidney disease (CKD), using data from National Prescribing Service (NPS) MedicineWise's MedicineInsight dataset, and compare this dataset to the 2011–2012 Australian Health Survey's (AHS) CKD prevalence estimates. METHODS: This was a cohort study using deidentified, longitudinal, electronic health record data collected from 329 practices and 1 483 416 patients distributed across Australia, from 1 June 2013 until 1 June 2016. Two methods were used to calculate the CKD prevalence. One used the same method as used by the 2011–2012 AHS, based on one estimate of the estimated glomerular filtration rate (eGFR) or albumin/creatinine ratios (ACR). The other defined CKD more rigorously using eGFR or ACR results at least 90 days apart. RESULTS: In 2016, of 1 310 602 active patients, 710 674 (54.2%) did not have an eGFR or ACR test, while 524 961 (40.1%) had an eGFR or ACR test but did not meet AHS criteria for CKD. Age–sex adjusted rates of CKD (compared to AHS) were CKD 1–0.45% (3.9%), CKD 2–0.62% (2.5%), CKD 3a: 3.1% (2.7%), CKD 3b: 1.14% (0.6%), CKD 4–5: 0.41% (0.3%). The CKD cohort defined more rigorously using eGFR and ACR measures >90 days apart, had comorbidities of atrial fibrillation (30.5%), cardiovascular disease (25.0%), diabetes mellitus (17.1%) and hypertension (14.8%). CONCLUSION: The MedicineInsight dataset contains valuable and timely information about Australian patients with CKD, and provides prevalence estimates similar to those from AHS data. John Wiley & Sons Australia, Ltd 2018-12-13 2019-10 /pmc/articles/PMC6790712/ /pubmed/30467996 http://dx.doi.org/10.1111/nep.13537 Text en © 2018 The Authors Nephrology published by John Wiley & Sons Australia, Ltd on behalf of Asian Pacific Society of Nephrology This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Articles
Radford, Janette
Kitsos, Alex
Stankovich, Jim
Castelino, Ronald
Khanam, Masuma
Jose, Matthew
Peterson, Gregory
Saunder, Timothy
Wimmer, Barbara
Razizaidi, Tabish
Epidemiology of chronic kidney disease in Australian general practice: National Prescribing Service MedicineWise MedicineInsight dataset
title Epidemiology of chronic kidney disease in Australian general practice: National Prescribing Service MedicineWise MedicineInsight dataset
title_full Epidemiology of chronic kidney disease in Australian general practice: National Prescribing Service MedicineWise MedicineInsight dataset
title_fullStr Epidemiology of chronic kidney disease in Australian general practice: National Prescribing Service MedicineWise MedicineInsight dataset
title_full_unstemmed Epidemiology of chronic kidney disease in Australian general practice: National Prescribing Service MedicineWise MedicineInsight dataset
title_short Epidemiology of chronic kidney disease in Australian general practice: National Prescribing Service MedicineWise MedicineInsight dataset
title_sort epidemiology of chronic kidney disease in australian general practice: national prescribing service medicinewise medicineinsight dataset
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790712/
https://www.ncbi.nlm.nih.gov/pubmed/30467996
http://dx.doi.org/10.1111/nep.13537
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